Cold Spring Harbor Laboratory (CSHL) President and CEO Bruce Stillman has been dissecting DNA replication, a critical step in cell division, since the 1980s. His lab studies how Origin Recognition Complexes—ORCs—coordinate ...
Molecular & Computational biology
Mar 23, 2021
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189
Over evolutionary time scales, a single gene may acquire different roles in diverging species. However, revealing the multiple hidden roles of a gene was not possible before genome editing came along. Cold Spring Harbor Laboratory ...
Cell & Microbiology
Mar 4, 2021
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28
Corn—or maize—has changed over thousands of years from weedy plants that make ears with less than a dozen kernels to the cobs packed with hundreds of juicy kernels that we see on farms today. Powerful DNA-editing techniques ...
Biotechnology
Feb 22, 2021
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811
Corn hasn't always been the sweet, juicy delight that we know today. And, without adapting to a rapidly changing climate, it is at risk of losing its place as a food staple. Putting together a plant is a genetic puzzle, with ...
Plants & Animals
Jan 26, 2021
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99
Transforming a fertilized egg into a fully functional adult is a complicated task. Cells must divide, move, and mature at specific times. Developmental genes control that process, turning on and off in a choreographed way. ...
Cell & Microbiology
Dec 22, 2020
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54
Cold Spring Harbor Laboratory (CSHL) scientists developed the world's first mobile genome sequence analyzer, a new iPhone app called iGenomics. By pairing an iPhone with a handheld DNA sequencer, users can create a mobile ...
Biotechnology
Dec 7, 2020
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1757
Nearly 200 years ago, Charles Darwin noted striking diversity among the finches of the Galapagos Islands, and his observations helped him propose the role of natural selection in shaping species. Today, some biologists focus ...
Plants & Animals
Nov 18, 2020
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66
The most basic activity of a living thing is to turn one copy of its genome into two copies, crafting one cell into two. That replication event begins with a set of proteins—the Origin of Replication Complex (ORC). And, ...
Biotechnology
Sep 16, 2020
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12
Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)—annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes. ...
Biotechnology
Jul 29, 2020
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16
For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain ...
Cell & Microbiology
Jun 30, 2020
0
265
