Biologists reveal novel drug binding site in NMDA receptor subunit

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly ...

Reference Genome of Maize Published (w/ Podcast)

(PhysOrg.com) -- A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory scientists culminated today in publication of a landmark series of papers in the journal Science revealing in unprecedented ...

Polymers 'click' together using green chemistry

SOF4 is a gas that was discovered over a hundred years ago but is rarely used because it is difficult to prepare and highly reactive. Now a collaboration of chemists including Cold Spring Harbor Laboratory (CSHL) Professor ...

How to tune out common odors and focus on important ones

Quantitative biologists at CSHL have figured out how a fly brain learns to ignore overwhelmingly prevalent, mundane odors to focus on more important ones. It's an important step towards understanding how our senses work and ...

New cell subtypes classified in mouse brain

It's been estimated that the human brain contains roughly 100 billion neurons, together completing countless tasks through countless connections. So how do we make sense of the roles each of these neurons play? As part of ...

ENCODE3: Interpreting the human and mouse genomes

Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)—annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes. ...

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