Technology monitors myriad molecules

May 07, 2007

A U.S. scientist has created a computer chip consisting of thousands of electrodes yielding molecules that bind to receptor sites.

Chemistry Professor Kevin Moeller of Washington University in St. Louis said the electrodes on the chip can be used to monitor the biological behavior of up to 12,000 molecules at the same time.

Moeller and colleagues are pioneering new methods for building libraries of small molecules on addressable electrode arrays so the molecules can be monitored in real-time and, in turn, used to probe the binding requirements of drug receptor sites.

The electrochemically addressable chips represent a new environment for synthetic organic chemistry, he said, changing the way chemists and biomedical researchers make molecules, build molecular libraries and understand the mechanisms by which molecules bind to receptor sites.

"We believe we can move most of modern synthetic organic chemistry to this electrochemically addressable chip," said Moeller. "It's a tool, still being developed, to map receptors. We're right at the cusp of things."

Moeller discussed the technology in a recent article in the Journal of the American Chemical Society and presented his work Monday in Chicago during the 211th National Meeting of the Electrochemistry Society.

Copyright 2007 by United Press International

Explore further: Chemists create nanofibers using unprecedented new method

add to favorites email to friend print save as pdf

Related Stories

Tough foam from tiny sheets

34 minutes ago

Tough, ultralight foam of atom-thick sheets can be made to any size and shape through a chemical process invented at Rice University.

India's Flipkart raises $1 bn to tackle Amazon

1 minute ago

India's top e-commerce company Flipkart said Tuesday it had raised $1 billion (60 billion rupees) in funds as it battles US giant Amazon for supremacy in the hyper-competitive local market.

Rare Sri Lankan leopards born in French zoo

41 minutes ago

Two rare Sri Lankan leopard cubs have been born in a zoo in northern France, a boost for a sub-species that numbers only about 700 in the wild, the head of the facility said Tuesday.

Recommended for you

Free pores for molecule transport

9 hours ago

Metal-organic frameworks (MOFs) can take up gases similar to a sponge that soaks up liquids. Hence, these highly porous materials are suited for storing hydrogen or greenhouse gases. However, loading of many ...

User comments : 0