The sixth sense -- your place in space

Apr 03, 2006

In addition to the familiar five senses—touch, sight, smell, hearing, and taste—scientists know of a sixth sense called proprioception It 's the sense of where your body is in space that allows you to touch your nose even with your eyes closed. Proprioception (PRO-pree-oh-ception) also informs balance and how to put one foot in front of the other to walk without looking at your feet.

LSI research assistant professor Shawn Xu and his colleagues discovered that the "sixth sense" is present in the model organism C. elegans, a 1 millimeter nematode,and have been using worms to study proprioception.

They have recently discovered some neurons that possibly regulate stretch receptors which tell the body how to move. For patients with Parkinson 's disease, these stretch receptors are thought to be involved in the loss of movement control, so finding a neuron that can tweak these signals could be a step towards developing new Parkinson 's treatments.

Xu focuses his research on a superfamily of critical, but poorly understood, calcium-permeable ion channels, the TRP channels. Using C. elegans, he found a communication channel between neuron and muscle, TRP-4, which plays a role in movement. Xu 's research shows that TRP-4 acts in a neuron called DVA that regulates how sensory-motor function is put together to produce movement. It controls locomotion, providing a unique mechanism whereby a single neuron can fine-tune motor activity.

"We are really studying neuronal signaling and the movement behavior, " Xu said. "There are many channels and they are the same in worms and humans. "

The paper "A C. elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue," by Wei Li, Zhaoyang Feng, Paul W. Sternberg, and X. Z. Shawn Xu, was published in the journal Nature, March 29, 2006.

Source: University of Michigan

Explore further: Greenland darkening to continue, predicts CCNY expert Marco Tedesco

Related Stories

'Map spam' puts Google in awkward place

1 hour ago

Google was re-evaluating its user-edited online map system Friday after the latest embarrassing incident—an image of an Android mascot urinating on an Apple logo.

Team develops faster, higher quality 3-D camera

2 hours ago

When Microsoft released the Kinect for Xbox in November 2010, it transformed the video game industry. The most inexpensive 3-D camera to date, the Kinect bypassed the need for joysticks and controllers by ...

Recommended for you

Study finds we think better on our feet, literally

17 hours ago

A study from the Texas A&M Health Science Center School of Public Health finds students with standing desks are more attentive than their seated counterparts. In fact, preliminary results show 12 percent ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.