Microbiotic technology developed for microinjection of zebrafish embryos

Sep 12, 2007

Funded by an NSERC Idea to Innovations grant and an Ontario Early Researcher Award, Prof. Yu Sun’s group, the Advanced Micro and Nanosystems Laboratory at the University of Toronto recently developed a microrobotic technology for automated microinjection of zebrafish embryos.

Based on computer vision and motion control, the automated microrobotic system is capable of immobilizing a large number of zebrafish embryos into a regular pattern within seconds and injecting 15 embryos (chorion unremoved) per minute with a success rate, survival rate, and phenotypic rate all close to 100%. The system and performance were reported in the journal PLoS ONE in an article entitled, “A Fully Automated Robotic System for Microinjection of Zebrafish Embryos.”

Zebrafish is a model organism widely used in life sciences. High-speed injection of zebrafish embryos is important for screening genes in genetics and drug molecules in drug discovery. The automated microrobotic system proves itself as a reliable tool for determining gene functions and more generally, for facilitating large-scale molecule screening.

Source: Public Library of Science

Explore further: Synthetic biology, genetic engineering and you: Two-component signaling pathways as elements in synthetic circuit design

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Warming world may spell bad news for honey bees

3 hours ago

Researchers have found that the spread of an exotic honey bee parasite -now found worldwide - is linked not only to its superior competitive ability, but also to climate, according to a new study published ...

Students create microbe to weaken superbug

4 hours ago

A team of undergraduate students from the University of Waterloo have designed a synthetic organism that may one day help doctors treat MRSA, an antibiotic-resistant superbug.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.