Molecular Cell aims to publish the best research in molecular biology.
Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the ...
Biotechnology
Dec 13, 2018
19
6427
The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he ...
Biotechnology
Sep 3, 2021
2
1511
While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins.
Cell & Microbiology
Dec 4, 2023
0
323
Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
Biotechnology
Jul 11, 2018
0
526
Scientists at the University of Cambridge, in collaboration with Justus-Liebig University, Germany, have uncovered how the genome of SARS-CoV-2—the coronavirus that causes COVID-19—uses genome origami to infect and replicate ...
Cell & Microbiology
Nov 5, 2020
0
619
Many of the world's most common or deadly human pathogens are RNA-based viruses—Ebola, Zika and flu, for example—and most have no FDA-approved treatments. A team led by researchers at the Broad Institute of MIT and Harvard ...
Cell & Microbiology
Oct 10, 2019
3
3219
Serotonin (5-HT) is one of the main neurotransmitters in the human central nervous system and peripheral nervous system. It helps regulate appetite, memory, cognition and mood through serotonin receptors (5-HTR).
Cell & Microbiology
Jun 17, 2022
0
473
Tardigrades, the microscopic animals also known as water bears and moss piglets, have captured the imagination of scientists for almost 250 years, thanks to their Muppet-like appearance and their ability to survive extreme ...
Cell & Microbiology
Mar 16, 2017
2
725
When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in ...
Cell & Microbiology
Mar 9, 2023
0
139
A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.
Biotechnology
Feb 9, 2024
0
286
