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Unlocking the hidden pocket on a billion‑dollar drug target

For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, ...

Five-minute test spots PFAS down to parts-per-trillion

When Sandia scientists Ryan Davis and Nathan Bays set out to find a better way to absorb and degrade PFAS in water sources, they kept running into the same issue: Detecting the chemicals in samples took too long. So, they ...

Upconversion materials: A new frontier in solar water-splitting

Solar water splitting is one of the most direct ways to produce green hydrogen using sunlight. However, most photocatalysts and photoelectrodes absorb only a limited portion of solar radiation, mainly ultraviolet and part ...

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Analytical Chemistry
Cleaner water, longer-lasting devices: New benchmark measures electrocatalysis oxidants in real time
Analytical Chemistry
The secret lives of catalysts: How microscopic networks power reactions
Polymers
Polymer-chemistry dataset created for training AI models
Biochemistry
New peptide catalyst enables stereoselective head-to-tail macrocycle synthesis
Analytical Chemistry
From water splitting to H₂O₂: A new method narrows carbon nitride photocatalyst design
Biochemistry
Hard-to-make diastereomers: How a cage-like allyl reagent changes the outcome
Biochemistry
Chemically 'stapled' peptides used to target difficult-to-treat cancers
Analytical Chemistry
A community-driven standard for reporting metal–organic framework syntheses
Analytical Chemistry
Chemists rapidly assemble fusicoccadiene, a complex fungal molecule tied to cancer research
Analytical Chemistry
How to train your catalyst, one atom at a time
Biochemistry
Chemists create complex DNA structures without hydrogen bonds
Analytical Chemistry
A crystal that 'comes alive': Heat-driven bubbles push it forward while it changes fluorescence color
Biochemistry
Chemists create iridium compounds for the synthesis of 'smart' antitumor drugs
Analytical Chemistry
Identifying potential drug candidates with deep learning virtual screening
Analytical Chemistry
Scientists synthesize stable N₄ radical anions under ambient conditions
Biochemistry
Nutri-Score labels do not reflect true nutritional quality of soluble cocoa, study shows
Analytical Chemistry
AI toolkit turns microscopy images into multi-feature microstructure datasets
Analytical Chemistry
Carbon-based catalyst can use sunlight to degrade PFAS
Analytical Chemistry
Using high-energy sparks to degrade pollutants without generating waste
Biochemistry
Turning over a new leaf in analyses of natural products

Other news

Astronomy
Galactic islands of tranquility: 'Little red dots' may have brewed life's building blocks
Earth Sciences
Climate change is slowing Earth's spin at unprecedented rate compared to past 3.6 million years
Condensed Matter
Palm-sized superconducting magnet achieves 42 tesla, rivaling the world's biggest
Archaeology
Researcher uncovers Zoroastrian 'ripples' in Jewish documents from ancient Egypt
Astronomy
We are not alone: Our sun escaped together with stellar 'twins' from galaxy center
Ecology
Shell game: How oysters enlist help from microbes
Plants & Animals
New study of global reef growth over past 12,000 years offers insights into impact of rising ocean temperatures
Plants & Animals
The bizarre sex life of mayflies: Micro-CT scans reveal ins and outs of swarm Kamasutra
Astronomy
NASA's tiny spacecraft sends first exoplanet images
Archaeology
Upper Egypt site has now yielded more than 43,000 inscribed pot sherds, a record-breaking trove of information
Cell & Microbiology
Turning penicillin into a lethal force against bacteria again
Ecology
Satellite data suggest Sundarbans mangroves are losing resilience
Plants & Animals
Pollen-replacing feed strengthens honey bee colonies, long-term study confirms
Nanophysics
Allowing atoms to come and go can open the door to better materials modeling
Cell & Microbiology
Capsule technology opens new window into individual cells
Astronomy
AI accelerates elucidation of nuclear forces with explosive neutron star data
Plants & Animals
Wolves kill—and ravens remember where
Archaeology
Musicologists map medieval chant tropes to 9th-century political borders
Plants & Animals
Can rapid evolution 'rescue' species from climate change?
Evolution
Ancient DNA sequences that control gene function across plant evolution uncovered