DNA sequencing is a set of laboratory methods for determining the precise linear order of nucleotides (A, C, G, T) in a DNA molecule. Core methodological classes include Sanger sequencing, which uses chain-terminating dideoxynucleotides and capillary electrophoresis for high-fidelity, low-throughput analysis, and next-generation sequencing (NGS) platforms, which employ massively parallel sequencing-by-synthesis, sequencing-by-ligation, or nanopore-based readout for high-throughput, genome-scale applications. These methods entail library preparation, clonal or single-molecule amplification (except in true single-molecule approaches), signal detection, and computational base-calling, followed by quality control and downstream bioinformatic analysis.
The spectacled cobra (Naja naja) is one of India's "big four" snakes responsible for most serious snakebite cases. It is currently considered one species, which lives across much of South Asia, with regional differences in ...
The Wellcome Sanger Institute's Tree of Life program plans to accelerate publication of genome notes from approximately 30 per month to 200, expanding access to research that is supporting advances in agriculture, conservation ...
Ecology
Oct 14, 2026
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A new study by researchers at the University of South Florida and Florida Atlantic University has demonstrated that a DNA sequencing tool can rapidly identify harmful algae in coastal waters, offering a new approach for monitoring ...
Ecology
Oct 14, 2026
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A discovery has led to the first confirmed records of recreational catches of Pacific bluefin tuna (Thunnus orientalis) in Victorian waters.
Plants & Animals
Oct 14, 2026
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For decades, scientists have been able to look at individual moments in the development of an embryo: a snapshot of a developing brain, a picture of how the heart takes shape or a glimpse of cells beginning to form the nervous ...
Cell & Microbiology
Oct 13, 2026
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Across mammals, larger species typically have longer lifespans, ranging from only a couple of years for mice to almost 200 years for some whales.
Molecular & Computational biology
Oct 8, 2026
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Growing inside each of us is a cellular family tree. Every one of the 37 trillion cells in our body is generated from another cell, going all the way back to a single fertilized egg. Much like we can draw a family tree tracking ...
Cell & Microbiology
Oct 8, 2026
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18
Identifying the favorite snacks of one of Australia's cutest animals no longer needs to rely on guesswork or picking apart their poop, according to University of the Sunshine Coast research. Although the shortened title of ...
Plants & Animals
Oct 8, 2026
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9
Tiny single-celled organisms help keep lakes clear, but some can also contaminate the water. An international research team has analyzed DNA data from 362 lakes to create the first global genome atlas of these organisms. ...
Ecology
Oct 7, 2026
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DNA analyses of ancient remains have revealed a previously unknown extinct bovine species that inhabited southern Siberia during and even before the last ice age. The extinct species was related to modern yaks but followed ...
Plants & Animals
Oct 5, 2026
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