New AIDS drug shows 'phenomenal' results

Jan 02, 2007

AIDS researchers said a new drug shows promise for inhibiting the HIV virus in patients new to treatment or those currently taking a drug cocktail.

Clinical studies of the drug, called an integrase inhibitor, showed that, when combined with two existing drugs, it reduced the virus to undetectable levels in nearly 100 percent of HIV patients prescribed a drug regimen for the first time, The Los Angeles Times said Tuesday. It had a similar effect in 72 percent of salvage therapy patients, who take a mixture of existing medications aimed at stalling the virus until new drugs appear.

The drug essentially prevents the virus' DNA from integrating with a host's cells, inhibiting its ability to replicate itself.

The U.S. Food and Drug Administration should approve it in mid-2007. Manufacturer Merck & Co. is making it available sooner to patients in desperate straits.

"They tested it on some people who were in deep, deep salvage therapy, and even those people did remarkably well," Dr. Steven Deeks, a University of California, San Francisco salvage therapy authority, told the Times. "It seems to be a truly phenomenal drug that ... is changing the whole way we think about the management of these patients."

Copyright 2007 by United Press International

Explore further: HIV testing yields diagnoses in Kenya but few seek care

add to favorites email to friend print save as pdf

Related Stories

Metabolic errors can spell doom for DNA

Jan 31, 2012

Many critical cell functions depend on a class of molecules called purines, which form half of the building blocks of DNA and RNA, and are a major component of the chemicals that store a cell’s energy. ...

A new approach to medicine

Sep 24, 2010

(PhysOrg.com) -- University of Connecticut researchers are exploring how to take a patient's own cells, re-engineer them, and replace them in the body.

Recommended for you

HIV testing yields diagnoses in Kenya but few seek care

20 hours ago

Between December 2009 and February 2011, health workers with the AMPATH Consortium sought to test and counsel every adult resident in the Bunyala subcounty of Kenya for HIV. A study in the journal Lancet HIV reports that the campaign yielded more than 1,300 new positive diagnoses, but few of those new ...

The adaptability of pathogens

Jan 28, 2015

Drug-resistant HIV viruses can spread rapidly. This is the conclusion of a study conducted as part of the SWISS HIV Cohort Study, which is supported by the SNSF. Only the continuous introduction of new drugs can stop the ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.