Measles virus used to kill cancer cells

Oct 31, 2006

U.S. researchers are starting the second of several pending molecular medicine studies in patients using measles to kill cancer cells.

Mayo Clinic Cancer Center scientists opened the new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme -- a largely untreatable brain tumor.

"We are looking at better ways to treat some of the most lethal cancers," said Dr. Eva Galanis, oncologist and lead researcher on the glioblastoma multiforme project in the measles virus investigation. "We have shown in the laboratory and in several animal models that measles virus strains can significantly shrink glioma tumors and prolong animal survival."

The Mayo Clinic says its pursuit of oncolytic measles vaccine strains for cancer treatment is unique, growing from the most basic laboratory science to a sophisticated therapy being tested in several tumor types, including glioblastoma multiforme, recurrent ovarian cancer and multiple myeloma.

The glioblastoma multiforme study, which started Tuesday, is designed to test the safety of the virus for the treatment of gliomas and enable biological monitoring of anti-tumor activity.

Copyright 2006 by United Press International

Explore further: PDE-5 inhibitors tied to prostate cancer biochemical recurrence

add to favorites email to friend print save as pdf

Related Stories

Standalone wireless info display device an easy fit

42 minutes ago

A Latvian team has come up with a good-looking WiFi display device, connecting to the Internet using WiFi, which runs on a high-capacity built-in battery and tracks what's important to you. This is a standalone ...

Technology improves avalanche gear for backcountry skiers

2 hours ago

As outdoor recreation companies increasingly cater to skiers and snowboarders who like to venture beyond the groomed slopes at ski resorts and tackle backcountry terrain, they've put a special emphasis on gear and equipment ...

The elephant poaching business in numbers

2 hours ago

From the pittance paid to local poachers to a multi-billion dollar industry, here are some of the key numbers related to Africa's endangered elephants:

UN moves toward major treaty for ocean biodiversity

2 hours ago

UN member states agreed Saturday to begin negotiations on a treaty to protect marine biodiversity in ocean areas extending beyond territorial waters, in a move heralded by environmental organizations.

Recommended for you

The future of precision immunology

38 minutes ago

In his State of the Union address, President Obama announced a new precision medicine initiative to work on finding a cure for cancer and other diseases. Howard L. Kaufman, a leading immunotherapy expert ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.