Study finds mild cognitive impairment is more common in men

Sep 06, 2010

A new Mayo Clinic study found that the prevalence of mild cognitive impairment was 1.5 times higher in men than in women. The research, part of the Mayo Clinic Study of Aging, also showed a prevalence rate of 16 percent in the population-based study of individuals aged 70-89 without dementia who live in Olmsted County, Minn. The study will be published in the September issue of Neurology.

A new study shows that mild cognitive impairment (MCI) may affect more men than women. The research is published in the September 7, 2010, print issue of Neurology, the medical journal of the American Academy of Neurology.

Mild cognitive impairment is a condition in which people have problems with memory or thinking beyond that explained by the normal rate of aging. The study found that MCI was 1.5 times higher in men compared to women. MCI often leads to Alzheimer's disease.

"This is the first study conducted among community-dwelling persons to find a higher prevalence of MCI in men," said study author Ronald Petersen, MD, PhD, with the Mayo Clinic in Rochester, Minn. "If these results are confirmed in other studies, it may suggest that factors related to gender play a role in the disease. For example, men may experience cognitive decline earlier in life but more gradually, whereas women may transition from normal memory directly to dementia at a later age but more quickly."

For the study, 2,050 people between the ages of 70 to 89 in Olmstead County, Minn. were interviewed about their memory and their medical history and tested on their memory and thinking skills.

The study found that nearly 14 percent of participants had mild cognitive impairment, about 10 percent had dementia and 76 percent of those tested had normal memory and thinking skills. A total of 19 percent of men had mild cognitive impairment, compared to 14 percent of women.

"Our results, showing combined rates of MCI and dementia at 22 percent highlight the public health impact these conditions have and the importance of finding treatments for them," said Petersen. People in the study who had a low level of education or were never married also had a higher rate of MCI.

Explore further: Know the brain, and its axons, by the clothes they wear

add to favorites email to friend print save as pdf

Related Stories

Alzheimer's disease risks are gender specific

May 01, 2008

The risks of developing Alzheimer’s disease differ between the sexes, with stroke in men, and depression in women, critical factors, suggests research published ahead of print in the Journal of Neurology Neurosurgery an ...

Recommended for you

Know the brain, and its axons, by the clothes they wear

Apr 18, 2014

(Medical Xpress)—It is widely know that the grey matter of the brain is grey because it is dense with cell bodies and capillaries. The white matter is almost entirely composed of lipid-based myelin, but ...

Turning off depression in the brain

Apr 17, 2014

Scientists have traced vulnerability to depression-like behaviors in mice to out-of-balance electrical activity inside neurons of the brain's reward circuit and experimentally reversed it – but there's ...

Rapid whole-brain imaging with single cell resolution

Apr 17, 2014

A major challenge of systems biology is understanding how phenomena at the cellular scale correlate with activity at the organism level. A concerted effort has been made especially in the brain, as scientists are aiming to ...

User comments : 2

Adjust slider to filter visible comments by rank

Display comments: newest first

bottomlesssoul
not rated yet Sep 07, 2010
That variation is in the noise if I assume a 50/50 split between men and women and each has the same odds. It gives about +/- 3% or 66% of the time the natural variation between samples will be within 6%.

If the signal is this weak it needs a much larger sample size, at least twice as large.
Radman
not rated yet Sep 08, 2010
@bottomlesssoul - there is a Sminton web comic about this research paper that appears to have the same opinion as you!

http://www.pixton...8wp5sa9u

More news stories

Cancer stem cells linked to drug resistance

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered ...

Making graphene in your kitchen

Graphene has been touted as a wonder material—the world's thinnest substance, but super-strong. Now scientists say it is so easy to make you could produce some in your kitchen.