Conservative surgery not inferior to nephrectomy

Apr 19, 2010

The latest results from the European Organisation for Research and Treatment of Cancer (EORTC) 30904 study were presented in a plenary session today at the Anniversary EAU Congress, which showed that conservative surgery is not inferior to radical renal surgery or nephrectomy.

"Few patients progressed during the study, nine in the radical arm and 12 in the conservative arm," Prof. Hein van Poppel said in his concluding remarks. Van Poppel issued the EORTC results during the plenary session on , a study which examined partial versus radical nephrectomy in .

The EORTC 30904 study involved 541 patients who were randomised, 273 in the radical arm and 268 treated with conservative surgery. Four patients were clinically ineligible, whilst 139 patients were pathologically ineligible. The median follow-up was around 9.3 years.

Amongst the study's pertinent findings were:

  • Few patients progressed during the study, nine in the radical arm and 12 in the conservative arm
  • 117 deaths
12 due to RCC: 4 in radical and 8 in conservative

3 due to surgery: 1 in radical and 2 in conservative

  • Overall survival (OS) is shorter on the conservative arm for all randomized patients (p=0.032)
  • OS of RCC patients is not different (p=0.072)
  • OS of Clinically and pathologically eligible patients is not different (p=0.173)
  • Side effects: nephron-sparing surgery is safe with a slightly higher complication rate than after radical nephrectomy

Explore further: Seth Mnookin on vaccination and public health

Provided by European Association of Urology

not rated yet
add to favorites email to friend print save as pdf

Related Stories

How less can be more when treating some kidney cancers

Jan 09, 2008

A new Mayo Clinic study suggests that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival compared with an operation that removes the tumor but leaves the kidney ...

Recommended for you

Uganda on defensive over medical 'brain drain' uproar

8 hours ago

Uganda's government on Tuesday hit back at mounting criticism of plans to 'export' over 200 health workers to the Caribbean, insisting it was only seeking to regulate an existing labour market and prevent abuses.

Seth Mnookin on vaccination and public health

Mar 02, 2015

Seth Mnookin, an assistant professor of science writing and associate director of MIT's Graduate Program in Science Writing, is the author of "The Panic Virus: The True Story Behind the Vaccine-Autism Controversy" ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.