Thiopurine therapy improves quality of life

Mar 01, 2010

Patients with inflammatory bowel diseases (IBDs) such as Crohn's disease or ulcerative colitis do perceive a benefit from thiopurine treatment. A report in the open access journal BMC Gastroenterology has demonstrated improved health-related quality of life in 92 IBD patients.

Guillermo Bastida worked with a team of researchers from La Fe Hospital, Valencia, Spain, to investigate the controversial thiopurine treatment. He said, "The efficacy of thiopurines in the scenarios in which they are prescribed, either to induce or to maintain remission in IBD, is well proven. Their effect on has been a cause for concern however, with some reports suggesting that they can cause patients to perceive their lives as being more difficult while under treatment. However, the available data were scarce, so we carried out this clinical trial to study the problem more closely".

Bastida and his colleagues report that after one year of treatment with thiopurines, quality of life had improved significantly compared with baseline and all the scores were higher than those obtained at six months.

Explore further: Discovery could lead to new cancer treatment

More information: The effects of thiopurine therapy on health-related quality of life in Inflammatory Bowel Disease patients, Guillermo Bastida, Pilar Nos, Mariam Aguas, Marisa Iborra, Vicente Ortiz, Vicente Garrigues and Julio Ponce, BMC Gastroenterology (in press)

add to favorites email to friend print save as pdf

Related Stories

Early onset gene for inflammatory bowel diseases identified

Sep 02, 2008

A study of Crohn's disease and ulcerative colitis in children has identified a gene that influences whether children get these diseases early in life, and points to a potential new target for treatment. The findings of the ...

Recommended for you

Discovery could lead to new cancer treatment

9 hours ago

A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These findings could have implications ...

Is the HPV vaccine necessary?

15 hours ago

As the school year starts in full swing many parents wonder if their child should receive the HPV vaccine, which is recommended for girls ages 11-26 and boys 11-21. There are a lot of questions and controversy around this ...

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

deatopmg
1 / 5 (1) Mar 01, 2010
Crohn's disease is effectively controlled with low dose naltrexone for a very low cost, instead of expensive patented drugs like thiopurine. THere is some evidence that other IBDs are also controlled by LDN.