Study: Women need clot-busting therapy after stroke

Mar 01, 2010

New research shows women who don't receive a clot-busting drug after a stroke fare worse than men who are not treated. The study is published in the March 2, 2010, print issue of Neurology, the medical journal of the American Academy of Neurology.

"Women need to be treated for as soon as possible," said study author Michael D. Hill, MD, MSc, FRCPC, with the University of Calgary in Alberta, Canada. "We found that women who weren't treated had a worse quality of life after stroke than men. However, the good news is that women who were treated responded just as well as men to the treatment."

For the study, scientists examined information from a stroke database on 2,113 people who had experienced a stroke. Of those, 232 were treated with the clot-busting drug known as (tPA) and 44 percent were women. Men and women were separately placed in groups based on whether they received tPA within three hours after their stroke. After six months, the people were interviewed by phone about their ability to function and quality of life.

The study found that women who did not receive the clot-busting drug were 12 percent less likely than men to have a good outcome six months later, or 58 percent of the women compared to 70 percent of men. However, women who were treated with these medications fared about the same as men who took the clot-buster drug.

"There could be many reasons why women who weren't treated with the clot-busting drug fared worse than men, including biological reasons," said Hill. "One social reason may be that more than 30 percent of women were widowed compared to seven percent of men at the time of stroke, and therefore did not have a spouse who could act as a caregiver. Also, post-stroke depression is more common in than in men, which slows down recovery."

Explore further: New technique uses a genetic tool and light to view and map neuronal circuits

add to favorites email to friend print save as pdf

Related Stories

Arrival method, slow response often delay stroke care

Aug 08, 2008

Most stroke patients can't recall when their symptoms started or do not arrive at the hospital in a timely manner, so they cannot be considered for time-dependent therapies such as the clot-busting drug tissue plasminogen ...

More women than men having mid-life stroke

Jun 20, 2007

More women than men appear to be having a stroke in middle age, according to a study published June 20, 2007, in the online edition of Neurology, the medical journal of the American Academy of Neurology. Researchers say heart ...

Recommended for you

'Dimmer switch' for mood disorders discovered

14 hours ago

Researchers at University of California, San Diego School of Medicine have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as ...

How stress tears us apart

23 hours ago

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute (BMI) at EPFL have just highlighted a fundamental synaptic ...

User comments : 0