Plastics component affects intestine: study

Dec 14, 2009

The chemical Bisphenol A used in plastic containers and drinks cans has been shown for the first time to affect the functioning of the intestines, according to a French study published Monday.

National Institute of Agronomic Research researchers in Toulouse found the digestive tract of rats react negatively to even low doses of the chemical also called BPA, the Proceedings of the National Academy Sciences journal reported.

Their research, also conducted on human cells, found that the chemical lowered the permeability of the intestines and the immune system's response to digestive inflammation, it said.

BPA is used in the production of polycarbonated plastics and epoxy resins found in baby bottles, plastic containers, the lining of cans used for food and beverages, and in dental sealants.

Over 130 studies over the past decade have linked even low levels of BPA, which can leach from plastics, to serious health problems, , obesity and the early onset of puberty, among other disorders.

The French study focuses on the first organ to come in contact with the substance, the intestine.

The researchers orally administered doses of BPA to the rats that were equivalent to about 10 times less than the daily amount considered safe for humans, a statement from the Toulouse institute said.

They saw that BPA reduced the permeability of the instentinal lining through which water and essential minerals enter the body, it said.

They also found that newborn rats exposed to BPA in the uterus and during feeding have a higher risk of developing severe in adulthood.

The study "shows the very high sensitivity on the intestine of and opens news avenues for research" including to define new acceptable thresholds of the substance for humans, the institute said.

In May this year, the six major makers in the United States agreed to stop using the chemical.

(c) 2009 AFP

Explore further: Sexual fantasies: Are you normal?

add to favorites email to friend print save as pdf

Related Stories

Study: BPA research might have been bias

Apr 17, 2007

A U.S. scientific journal says bias might have resulted in inconsistent study results concerning the danger of a chemical found in many products.

Recommended for you

Independent safety investigation needed in the NHS

3 hours ago

The NHS should follow the lead of aviation and other safety-critical industries and establish an independent safety investigation agency, according to a paper published today by the Journal of the Royal Society of Medicine. The au ...

Sexual fantasies: Are you normal?

7 hours ago

Hoping for sex with two women is common but fantasizing about golden showers is not. That's just one of the findings from a research project that scientifically defines sexual deviation for the first time ever. It was undertaken ...

AMA 'Code of Ethics' offers guidance for physicians

13 hours ago

(HealthDay)—The American Medical Association (AMA) Code of Ethics and other articles provide guidance for physicians in relation to public health emergencies, according to a report from the AMA.

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

Caliban
1 / 5 (2) Dec 15, 2009
The article lead understates the case. Should read something more like: the compound bisphenol-A, found in virtually ALL prepackaged foods(including beverages)/food packaging....

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.