Sleep Apnea May Not Be Closely Linked to Heart Failure Severity

May 06, 2009

Obstructive sleep apnea (OSA) and central sleep apnea (CSA) are not markedly decreased in heart failure (HF) patients managed with beta-blockers and spironolactone, reports a study in the March issue of Journal of Cardiac Failure , published by Elsevier.

The study, “Prevalence and Physiological Predictors of Sleep Apnea in with and Systolic Dysfunction,” was authored by Dai Yumino, Hanqiao Wang, John S. Floras, Gary E. Newton, Susanna Mak, Pimon Ruttanaumpawan, John D. Parker, and T. Douglas Bradley.

As heart failure is a major public health concern, it is important to identify treatable conditions that may occur alongside it.  The high prevalence of OSA and CSA in patients with heart failure has been well recognized in recent years, but there is limited information about secular trends in its occurrence, despite important advances in the management of these patients since this phenomenon was recognized. 

The study involved 218 heart failure patients with reduced ejection fraction (mean 24.7%) who underwent sleep studies between 1997 and 2004. Overall 47% had moderate to severe OSA or CSA.  Both conditions were more prevalent in older age and in men.  OSA was associated with greater , whereas CSA was associated with atrial fibrillation, hypocapnia, and diuretic use.

These findings may have important implications for care HF patients with a prevalence of OSA and CSA because effective treatment of these sleep-related breathing disorders may be beneficial in addition to treatment with beta-blockers and sprionlactone.

"This study reemphasizes the high prevalence of sleep apnea, but unfortunately shows that despite the improvements in medical therapy and associated improvements in outcomes, the prevalence of sleep apnea has not diminished,” commented Barry M. Massie, M.D., Editor-in-Chief of Journal of .   “This may indicate that the severity of heart failure and the occurrence of sleep apnea are not closely linked, but that there are common risk factors for both, such as older age, male sex, and obesity.

More information: "Prevalence and Physiological Predictors of in Patients With Heart Failure and Systolic Dysfunction", Journal of Cardiac Failure, Volume 15, Issue 4, May 2009, Pages 279-285, http://www.elsevier.com/locate/cardfail

Source: Elsevier

Explore further: Africa's uneven health care becomes easy prey for Ebola

add to favorites email to friend print save as pdf

Related Stories

Procedure helps to eliminate sleep apnea

Oct 24, 2007

A procedure known as uvulopalatopharyngoplasty (UPPP) may help some patients improve or even eliminate their obstructive sleep apnea (OSA), according to a new study. The research, presented at CHEST 2007, the 73rd annual ...

Heart failure linked to cognitive impairment

Feb 05, 2009

Nearly half of patients with heart failure (HF) have problems with memory and other aspects of cognitive functioning, reports a new study published by Elsevier, in the February issue of Journal of Cardiac Failure .

Recommended for you

Africa's uneven health care becomes easy prey for Ebola

33 minutes ago

The disparity in African countries' ability to fight Ebola has left the continent fighting an uneven struggle against a disease that doesn't respect borders—yet relatively simple measures could help, experts say.

Ebola case stokes concerns for Liberians in Texas

1 hour ago

The first case of Ebola diagnosed in the U.S. has been confirmed in a man who recently traveled from Liberia to Dallas, sending chills through the area's West African community whose leaders urged caution ...

Is Australia prepared for Ebola?

4 hours ago

Australia needs to be proactive about potential disease outbreaks like Ebola and establish a national centre for disease control.

Dallas hospital confirms first Ebola case in US

10 hours ago

A patient at a Dallas hospital has tested positive for Ebola, the first case of the disease to be diagnosed in the United States, federal health officials announced Tuesday.

User comments : 0