Hormone Relaxine helps treat heart failure: study

Mar 30, 2009

Relaxine, a naturally occurring hormone that helps women adapt to pregnancy, is showing promise as a treatment for acute heart failure, a new study has found.

The research, conducted by scientists from the United States and Italy and presented here Sunday at an annual conference of the American College of Cardiology, said the helped patients to breathe more easily.

Given in addition to standard treatment, the hormone relaxin also reduced time for patients and prevented from worsening during hospitalization, the study said.

The hormone substantially relieved shortness of breath, or dyspnea, within just a few hours, an improvement that persisted over several days, the authors pointed out.

"Over 90 percent of patients with acute heart failure have dyspnea, and for the majority of these patients, it is the dyspnea that causes them to seek medical care," John Teerlink, a professor of clinical medicine at the University of California San Francisco, who authored the study.

"Consequently, improvement of dyspnea is an important and clinically relevant target of heart failure therapy."

Relaxin causes to dilate, taking pressure off the heart and increasing blood flow to the kidneys.

Marco Metra, a professor of medicine at the University of Brescia, Italy, and a co-author of the report, said relaxin was "a promising new therapy for acute heart failure that requires further testing in additional, larger ."

(c) 2009 AFP

Explore further: Are my muscular dystrophy drugs working?

add to favorites email to friend print save as pdf

Related Stories

New heart failure device is tested

Oct 17, 2006

Physicians at 50 U.S. medical facilities are taking part in a multinational clinical trial of a device designed to help heart failure victims.

Heart failure patients have higher risk of fractures

Oct 20, 2008

Heart failure patients are at higher risk for fractures, including debilitating hip fractures, than other heart patients and should be screened and treated for osteoporosis, Canadian researchers reported in Circulation: Jo ...

Recommended for you

Are my muscular dystrophy drugs working?

10 hours ago

People with muscular dystrophy could one day assess the effectiveness of their medication with the help of a smartphone-linked device, a new study in mice suggests. The study used a new method to process ...

Cell death proteins key to fighting disease

21 hours ago

Melbourne researchers have uncovered key steps involved in programmed cell death, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases.

Unlocking the secrets of pulmonary hypertension

Oct 30, 2014

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.