Hormone Relaxine helps treat heart failure: study

Mar 30, 2009

Relaxine, a naturally occurring hormone that helps women adapt to pregnancy, is showing promise as a treatment for acute heart failure, a new study has found.

The research, conducted by scientists from the United States and Italy and presented here Sunday at an annual conference of the American College of Cardiology, said the helped patients to breathe more easily.

Given in addition to standard treatment, the hormone relaxin also reduced time for patients and prevented from worsening during hospitalization, the study said.

The hormone substantially relieved shortness of breath, or dyspnea, within just a few hours, an improvement that persisted over several days, the authors pointed out.

"Over 90 percent of patients with acute heart failure have dyspnea, and for the majority of these patients, it is the dyspnea that causes them to seek medical care," John Teerlink, a professor of clinical medicine at the University of California San Francisco, who authored the study.

"Consequently, improvement of dyspnea is an important and clinically relevant target of heart failure therapy."

Relaxin causes to dilate, taking pressure off the heart and increasing blood flow to the kidneys.

Marco Metra, a professor of medicine at the University of Brescia, Italy, and a co-author of the report, said relaxin was "a promising new therapy for acute heart failure that requires further testing in additional, larger ."

(c) 2009 AFP

Explore further: Researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies

add to favorites email to friend print save as pdf

Related Stories

New heart failure device is tested

Oct 17, 2006

Physicians at 50 U.S. medical facilities are taking part in a multinational clinical trial of a device designed to help heart failure victims.

Heart failure patients have higher risk of fractures

Oct 20, 2008

Heart failure patients are at higher risk for fractures, including debilitating hip fractures, than other heart patients and should be screened and treated for osteoporosis, Canadian researchers reported in Circulation: Jo ...

Recommended for you

Strategy proposed for preventing diseases of aging

3 hours ago

Medicine focuses almost entirely on fighting chronic diseases in a piecemeal fashion as symptoms develop. Instead, more efforts should be directed to promoting interventions that have the potential to prevent ...

User comments : 0