Collagen injections can help some incontinence patients when surgery fails, researcher finds

Mar 17, 2009
Dr. Philippe Zimmern is a professor of urology and a UT Southwestern Medical Center researcher. Credit: UT Southwestern Medical Center

Collagen injections can benefit women who still suffer from stress urinary incontinence (SUI) even after urethral or periurethral surgery, a UT Southwestern Medical Center researcher has found.

"Patients with persistent or recurrent incontinence often do not wish to undergo another surgery," said Dr. Philippe Zimmern, professor of urology and the study's lead author. "The is also a good alternative for those who cannot afford recovery time from surgery or are too medically unfit or frail to undergo a second surgical intervention."

The prevalence of SUI is higher in women than men. While not life threatening, the condition can socially cripple those afflicted because of its embarrassing nature. Despite surgical advancements for treatment, existing procedures sometimes fail. Collagen has been used to treat SUI because its injection into the tissue surrounding the tightens the and stops urine from leaking.

The study, published in the February edition of the Journal of Urology, reviewed the records of patients who underwent periurethral collagen injection between January 2000 and December 2006. Patients were anesthetized briefly while the collagen was injected. Of the 31 patients, 93 percent (29 women) considered themselves clinically improved or cured.

Dr. Zimmern and his colleagues also used a 3-D to define the location and volume of collagen remaining in the urethral wall several months after the original injection. In patients who still suffered from SUI, a second injection was considered when the ultrasound indicated there was asymmetrical or low collagen volume. If the ultrasound showed adequate collagen levels but the patient still suffered from SUI, a different therapy was recommended.

"Women need to know they do not have to live with SUI," said Dr. Zimmern. "Although collagen injections might not work for everyone, the option is out there, and patients need to communicate with their physicians that they are afflicted with the condition to discover what treatments are possible."

Source: UT Southwestern Medical Center (news : web)

Explore further: Global Ebola conference seeks end to W.Africa outbreak

add to favorites email to friend print save as pdf

Related Stories

Sun-damaged skin does not improve with estrogen treatments

Sep 15, 2008

Treating the skin with estrogen can stimulate collagen production—which improves the appearance of the skin—in areas not typically exposed to the sun, according to new research from the University of Michigan Health System.

Inflammation worsens danger due to atherosclerosis

Jan 22, 2009

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis. The related report by Ovchinnikova et al, "T cell activation leads to reduced collagen maturation in atherosclerotic plaques ...

Recommended for you

Global Ebola conference seeks end to W.Africa outbreak

3 hours ago

Leaders of Ebola-hit countries in west Africa will attend an international conference in Brussels Tuesday to mobilise a final push to end the outbreak and ensure the delivery of nearly $5 billion in aid pledges.

High prevalence of HCV in baby boomers presenting to ER

13 hours ago

(HealthDay)—The prevalence of unrecognized chronic hepatitis C virus (HCV) is high among baby boomers presenting to the emergency department, according to a study published online Jan. 28 in Hepatology.

The hidden burden of dengue fever in West Africa

14 hours ago

Misdiagnosis of febrile illnesses as malaria is a continuing problem in Africa. A new study shows that in Ghana, dengue fever is circulating in urban areas and going undiagnosed. The authors of the study hope to use the findings ...

Teenager with stroke symptoms actually had Lyme disease

14 hours ago

A Swiss teenager, recently returned home from a discotheque, came to the emergency department with classic sudden symptoms of stroke, only to be diagnosed with Lyme disease. The highly unusual case presentation was published ...

Understanding lung disease in aboriginal Australians

15 hours ago

A new study has confirmed that Aboriginal Australians have low forced vital capacity—or the amount of air that can be forcibly exhaled from the lungs after taking the deepest breath possible. The finding may account for ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.