Can Taurine be a potent antioxidant drug in the future?

Sep 19, 2008

Taurine is a potent antioxidant with hepatoprotective effects. Organelle based changes in hepatocytes after taurine treatment in experimental liver fibrosis were searched systematically and organelle injury scores decreased were found to decrease significantly. Moreover, ultrastructural and histopathological scores in both groups were in strong correlation.

A research article to be published on August 21, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Mehmet Refik Mas from Gulhane School of Medicine in Turkey added a new information to their ongoing research works. Based on the fact that tissue health is directly related to functional recovery of the parenchyma cells during injury, the authors addressed the changes in major organelles in hepatocytes after administration of a hepatoprotective agent.

They not only demonstrated ultrastructural recovery with Taurine, but also reported that electron microscopy findings are reflected truly with light microscopy with the currently used scoring systems.

The results are to be helpful in future research in liver fibrosis.

The study is experimental; therefore, clinical confirmation is necessary. However, it can be postulated that similar changes occur in human hepatocytes in human chronic liver diseases if recovery can be attained.

Gulhane School of Medicine is a part of a large medical academy that was founded more than a century ago as a health staff source for the Turkish army. The academy currently supports not only institutional research projects but also keeps national and international scientific collaborations.

Source: World Journal of Gastroenterology

Explore further: Better living through mitochondrial derived vesicles

add to favorites email to friend print save as pdf

Related Stories

One Codex in open beta for genomic data search

2 hours ago

Data, data everywhere and now as ever researchers need the best tools to make the data useful. In medicine, searching through genomic data can take some time. A startup called One Codex hopes to make difference ...

After breakups, newspapers seek path forward

3 hours ago

Following an unprecedented series of spinoffs by major US media companies, the print news industry now faces a rocky future without financial support from deep-pocketed parent firms.

Recommended for you

Better living through mitochondrial derived vesicles

15 hours ago

(Medical Xpress)—As principal transformers of bacteria, organelles, synapses, and cells, vesicles might be said to be the stuff of life. One need look no further than the rapid rise to prominence of The ...

Zebrafish help to unravel Alzheimer's disease

16 hours ago

New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study by scientists at ...

Engineering new bone growth

19 hours ago

MIT chemical engineers have devised a new implantable tissue scaffold coated with bone growth factors that are released slowly over a few weeks. When applied to bone injuries or defects, this coated scaffold ...

User comments : 0