Of mice and men: similarities between skeletons of both

Oct 10, 2007

A new book by researchers at the Hebrew University of Jerusalem that details the skeletal structure of the mouse demonstrates a surprising similarity between mice and humans.

The book,”Micro-Tomorgrphic Atlas of the Mouse Skeleton,” was authored by a team from the Hebrew University Bone Laboratory consisting of Prof. Itai Bab, head of the laboratory; Dr. Carmit Hajbi-Yonissi and Dr. Yankel Gabet. Also participating in the writing of the book was Dr. Ralph Müller of the ETH of Zürich. The book, published by Springer of New York, provides great visual detail of the mouse skeletal structure, utilizing the technology of micro-tomographic imaging.

The authors observe that there are many areas of comparison between the mouse and human skeleton, with the exception of the facial, hand and foot bones. This is very important because, for example, mice, like people, suffer from osteoporosis. The significance of this lies in that research on osteoporosis in mice can have great relevance for and applications to humans. The same is true in relation to other problems related to fractures, skeletal development and illnesses, including testing of drugs.

According to Prof. Bab, earlier anatomical works on the mouse skeleton were based on visual observations only and are insufficient for purposes of modern research. Those books contained inexact material, insufficient detail, and only partial descriptions of the various skeletal components, said Bab.

Prof. Bab explained that in the last decade the new computerized micro-tomographic technology which has been developed provides excellent skeletal imaging. Using this technology, one can see two and three-dimensional images which show details down to the six-thousandth of a millimeter. The new atlas presents almost 200 such two and three-dimensional images, showing all external portions of the mouse skeleton and also the internal anatomy of the bones.

Also presented are three-dimensional images of the relationships between the bones at various joint positions. One chapter of the book, based on measurements of skeletons at various ages, describes the development of the skeleton and its aging and also the differences between males and females.

The micro-tomographic equipment used by the researchers was purchased by the Hebrew University. The purchase was partially supported by a grant from the Israel Science Foundation.

Source: The Hebrew University of Jerusalem

Explore further: Invasive procedures down with noninvasive prenatal testing

add to favorites email to friend print save as pdf

Related Stories

Washington takes on Uber with its own taxi app

12 hours ago

Washington is developing a smartphone app to enable its taxis to compete head-on with Uber and other ride-sharing services, the US capital's taxi commission said Friday.

Comet 67P/Churyumov-Gerasimenko in living color

12 hours ago

Rosetta's OSIRIS team have produced a color image of Comet 67P/Churyumov-Gerasimenko as it would be seen by the human eye. As anticipated, the comet turns out to be very grey indeed, with only slight, subtle ...

EU clean air, waste laws at risk

12 hours ago

EU Commission chief Jean-Claude Juncker faces a clash with lawmakers after leaked documents Friday revealed his plans to drop laws on clean air and waste recycling.

Recommended for you

Supplement maker admits lying about ingredients

Dec 17, 2014

Federal prosecutors say the owner and president of a dietary supplement company has admitted his role in the sale of diluted and adulterated dietary ingredients and supplements sold by his company.

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

Oderfla
not rated yet Feb 18, 2008
Please pass this on to any creationists you know.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.