Groundbreaking study on the progression of Alzheimer’s disease needs participants

Jan 07, 2011 By Erin White

Northwestern University Feinberg School of Medicine is enrolling participants for the first national study to detect Alzheimer’s disease in older people before they begin to have significant memory loss.

Researchers will use imaging techniques and biomarker measures in blood and cerebrospinal fluid specially developed to track changes in the living brain. The goal is to identify who is at risk for Alzheimer’s, track progression of the disease and devise tests to measure the effectiveness of potential interventions.

Northwestern Medicine’s Cognitive Neurology and Center (CNADC) is one of several study sites led by the National Institute on Aging. The study is an expansion of the National Institutes of Health’s Alzheimer’s Disease Neuroimaging Initiative.

“This is an important study to develop ways physicians can detect the disease before the person has overt memory loss,” said Diana Kerwin, the principal investigator of the study at CNADC and assistant professor of geriatrics at Feinberg. “The earlier we can detect disease the better chance there is to prevent or delay the memory loss from happening at all. Early diagnosis is really going to be key as far as making any further breakthroughs into the treatment of Alzheimer’s disease and other memory disorders.”

Potential include men and women aged 55 to 90 with early signs of that does not currently affect their daily lives. Participants without signs of cognitive problems also can enroll in the control group of the study.

“By taking part in the study, someone who has Alzheimer’s disease in their family or is concerned about their own memory would be contributing to our scientific understanding of the early markers of Alzheimer’s disease pathology in the brain and also normal aging,” Kerwin said.

Another important aspect of the study is the sharing of data soon after it is obtained. Imaging data is posted to a publicly accessible database available to qualified researchers worldwide.

Explore further: Experts question value of common superbug control practices

More information: To find out more about this study contact Kristine Lipowski, the study’s project coordinator, at: (312) 503-2486.

add to favorites email to friend print save as pdf

Related Stories

When 'senior moments' become something to worry about

Jan 07, 2011

(PhysOrg.com) -- It happens to all of us: You know you walked into a room for a reason, but you forget what it was. Or you see someone you’re acquainted with, but you can’t come up with her name. ...

Alzheimer's changes detectable in healthy elderly

Dec 22, 2010

A team of UCL researchers, part-funded by the Alzheimer's Research Trust, has discovered that combining spinal fluid testing with MRI scans could provide an early indication of a person’s risk of developing ...

Development of a safer vaccine for Alzheimer’s disease

Nov 17, 2010

A new vaccine protects against memory problems associated with Alzheimer's disease, but without potentially dangerous side effects, a new animal study reports. The research was presented at Neuroscience 2010, the annual meeting ...

Recommended for you

New analysis questions use of acute hemodialysis treatment

12 hours ago

A common approach to treating kidney failure by removing waste products from the blood did not improve survival chances for people who suddenly developed the condition, in an analysis led by experts at the University of Pittsburgh ...

WHO: West Africa Ebola death toll rises to 1,350 (Update)

13 hours ago

Riot police and soldiers acting on their president's orders used scrap wood and barbed wire to seal off 50,000 people inside their Liberian slum Wednesday, trying to contain the Ebola outbreak that has killed ...

User comments : 0