Menopausal hormone therapy may increase risk of ovarian cancer

Nov 09, 2010

Women planning on taking hormone therapy for the treatment of menopausal symptoms should be aware of a possible increased risk for ovarian cancer, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

"This study is consistent with previous recommendations that say if women are going to take hormones they should only take them in the short term," said Konstantinos Tsilidis, Ph.D., a postdoctoral fellow at the Cancer Epidemiology Unit at the University of Oxford.

Tsilidis and colleagues analyzed the European Prospective Investigation into Cancer and Nutrition, which included 126,920 women, of whom 424 were diagnosed with ovarian cancer over nine years of follow-up.

Although former use of hormone therapy was not associated with increased risk, current use of hormone therapy was linked with a 29 percent increased risk.

Risk levels did not differ by type of hormone therapy (estrogen only vs. plus progestin), specific hormonal constituents, regimens and routes of administration of , or by histology.

Explore further: Generation of tanners see spike in deadly melanoma

add to favorites email to friend print save as pdf

Related Stories

Hormone therapy raises cancer risk

Jan 16, 2008

Menopausal women who take hormone combinations for their symptoms are more likely to get an uncommon type of breast cancer much earlier than experts believed.

Study links obesity to elevated risk of ovarian cancer

Jan 05, 2009

A new epidemiological study has found that among women who have never used menopausal hormone therapy, obese women are at an increased risk of developing ovarian cancer compared with women of normal weight. Published in the ...

Recommended for you

Generation of tanners see spike in deadly melanoma

1 hour ago

(AP)—Stop sunbathing and using indoor tanning beds, the acting U.S. surgeon general warned in a report released Tuesday that cites an alarming 200 percent jump in deadly melanoma cases since 1973.

Penn team makes cancer glow to improve surgical outcomes

1 hour ago

The best way to cure most cases of cancer is to surgically remove the tumor. The Achilles heel of this approach, however, is that the surgeon may fail to extract the entire tumor, leading to a local recurrence.

Cancer: Tumors absorb sugar for mobility

14 hours ago

Cancer cells are gluttons. We have long known that they monopolize large amounts of sugar. More recently, it became clear that some tumor cells are also characterized by a series of features such as mobility or unlikeliness ...

User comments : 0