New tool 'cooks' cancer cells in inoperable brain tumors

Sep 30, 2010
Washington University neurosurgeons used an MRI-guided laser probe to treat hard-to-reach brain tumors at Barnes-Jewish Hospital for the first time last month. Credit: MONTERIS

Washington University neurosurgeons are tackling brain tumors at Barnes-Jewish Hospital with a new laser probe.

“This tool gives us a treatment for patients with tumors that were previously deemed inoperable,” says Eric C. Leuthardt, MD, assistant professor of neurological surgery and of neurobiology. “It offers hope to certain patients who had few or no options before.”

The tool is an MRI-guided high-intensity laser probe that “cooks” deep within the brain, while leaving surrounding brain tissue undamaged.

Barnes-Jewish Hospital is the third hospital in the United States to have the device.

Ralph G. Dacey Jr., MD, chief of neurosurgery at Washington University School of Medicine, and Leuthardt used the new system for the first time last month in a procedure on a patient with a recurrent brain located deep in the brain.

Previous surgeries coupled with the hard-to-reach location of the tumor made a standard tumor resection surgery impossible, says Leuthardt, also director of the Center for Innovation in and Technology at Washington University.

In last month’s procedure, the surgeons drilled a small burr hole about the diameter of a pencil through the patient’s skull, and then used MRI scans to guide the thin laser probe through the into the tumor.

Once inside the tumor, the laser discharged highly focused energy to “cook” and coagulate cancer cells, killing them. The MRI directed positioning of the laser and monitored in real time the discharge of energy to the tumor so healthy surrounding was left undamaged.

The tool, Monteris AutoLITT, received FDA approval for neurosurgical use in May 2009.

Explore further: Cancer survivors who smoke perceive less risk from tobacco

Related Stories

Fluorescent cancer cells to guide brain surgeons

Apr 03, 2009

Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain. Gliomas are often resistant to chemotherapy. These tumors grow fine extensions that infiltrate normal brain tissue and, in addition, ...

Recommended for you

Spicy treatment the answer to aggressive cancer?

6 hours ago

It has been treasured by food lovers for thousands of years for its rich golden colour, peppery flavour and mustardy aroma…and now turmeric may also have a role in fighting cancer.

Cancer survivors who smoke perceive less risk from tobacco

23 hours ago

Cancer survivors who smoke report fewer negative opinions about smoking, have more barriers to quitting, and are around other smokers more often than survivors who had quit before or after their diagnosis, according to a ...

Melanoma mutation rewires cell metabolism

23 hours ago

A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme, researchers at Winship Cancer Institute of Emory University have discovered.

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

fixer
not rated yet Oct 07, 2010
So how do they remove the dead tissue from the guys brain, or is it just left to rot?

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.