Multi-resistant skin bacteria spreading in hospitals

September 8, 2010

Genetically closely related skin bacteria that have developed resistance to several different antibiotics and that can cause intractable care-related infections are found and seem to be spreading within and between hospitals in Sweden.

This is established by Micael Widerstrom in the doctoral dissertation he is defending at Umea University in Sweden.

Coagulase-negative staphylococci (CNS) are that belong to the protective bacterial flora on the skin and seldom cause infections in healthy individuals. However, CNS, and especially Staphylococcus epidermidis, are a common cause of care-related infections, in particular infections following various types of prosthetic surgery. These infections are often difficult to treat, as certain strains of S. epidermidis have become resistant to most antibiotics (multi-resistant), and has a capacity to fasten on and form a so-called biofilm around catheters and inserted prostheses.

In his dissertation work, Micael Widerström found genetically closely related strains of multi-resistant S. epidermidis, in hospital patients from most of the eleven northern European hospitals studied, eight of them in Sweden. These closely related strains could not be found among healthy individuals in the community. The findings indicate that S. epidermidis, which has a special capacity to adapt to hospital environments, seems to be spreading within and between Swedish hospitals.

Current antibiotics and hygiene routines do not seem to prevent these strains from getting a foothold in hospital settings. The mechanisms for how these multi-resistant bacteria spread at our hospitals need to be charted if we are to be able to reduce the risk and cost of care-related infections.

The dissertation also describes another species of coagulase-negative staphylococcus, Staphylococcus saprophyticus. This is a common cause of that young and middle-aged women contract outside the environment. It is unclear how urinary tract infections caused by S. saprophyticus spread and whether certain genetic variants are especially likely to cause this type of infection. In the study, the same genetic variant of S. saprophyticus was found in urine samples from women in different countries and separated in time by several years. This indicates that certain genetic variants of S. saprophyticus are established as the cause of urinary tract infections and seem to be spreading within and among countries.

Explore further: FDA OKs urinary infection injectable drug

Related Stories

FDA OKs urinary infection injectable drug

October 18, 2007

The U.S. Food and Drug Administration announced approval Thursday of doripenem (Doribax) injections for the treatment of complex urinary tract infections.

Cranberry juice shows promise blocking Staph infections

September 1, 2010

Expanding their scope of study on the mechanisms of bacterial infection, researchers at Worcester Polytechnic Institute (WPI) have reported the surprise finding from a small clinical study that cranberry juice cocktail blocked ...

Recommended for you

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

(PhysOrg.com) -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...

Quantum Theory May Explain Wishful Thinking

April 14, 2009

(PhysOrg.com) -- Humans don’t always make the most rational decisions. As studies have shown, even when logic and reasoning point in one direction, sometimes we chose the opposite route, motivated by personal bias or simply ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.