Diabetes doubles risk of heart attack and strokes

Jun 25, 2010
Diabetes doubles risk of heart attack and strokes

(PhysOrg.com) -- Having diabetes doubles the risk of developing a wide range of blood vessel diseases, including heart attacks and different types of stroke, researchers in Cambridge have found.

Diabetes is now estimated to be responsible for 1 in every 10 deaths from cardiovascular disease, or about 325,000 cardiovascular deaths per year in all industrialised countries put together.

The results come from an analysis of 700,000 people by an international consortium led by Dr Nadeem Sarwar and Professor John Danesh of the University of Cambridge. The report is published in this week's and will be presented at the American Association's 70th Scientific Sessions in Orlando, Florida. The findings underscore the need to prevent diabetes in the face of increasing rates worldwide.

Cardiovascular disease is the leading cause of death globally, responsible for about 17 million deaths every year. Diabetes has long been recognised as a major risk factor for cardiovascular disease, but the extent of its effect on different blood vessel diseases has been debated. It has also been uncertain how much of the effect of diabetes on blood vessel diseases is due to higher levels of blood fats, , and obesity.

The new study involved a combined analysis of individual records on 700,000 people, each of whom was monitored for about a decade in 102 surveys conducted in 25 countries.

The findings show that having diabetes approximately doubles the risk of a wide range of blood vessel diseases. Perhaps surprisingly, however, only a small part of the effects of diabetes was explained by blood fats, blood pressure, and obesity. This finding suggests that diabetes may exert its harmful effects via additional routes.

According to Dr Sarwar: "Our findings highlight the need for better prevention of diabetes coupled with greater investigation of the mechanisms by which diabetes increases the risk of cardiovascular disease."

The study also found that in people without diabetes higher-than-average fasting blood were only weakly related to subsequent development of or strokes.

This finding argues against using information on blood glucose levels to help identify people at higher risk of heart attack or stroke. Dr Sarwar added: "Information on age, sex, smoking habits, blood pressure and is routinely collected to assess risk of developing cardiovascular disease. Our findings indicate that adding information on fasting blood glucose levels in people without diabetes does not provide significant extra help in assessing cardiovascular risk."

Explore further: Immigrant children given adult dose of hepatitis A vaccine

Related Stories

'Pre-diabetics' face heightened risk of heart disease

Mar 03, 2009

The study, published in the Journal of Clinical Endocrinology & Metabolism, was led by Jill P. Crandall, M.D., associate professor of clinical medicine and director of the Diabetes Clinical Trials Unit at Einstein.

Recommended for you

Philippines confirms second MERS case (Update)

4 hours ago

A foreigner who flew to the Philippines from the Middle East has become the second confirmed case of MERS in the country, the health department said Monday, as a deadly outbreak in South Korea spreads alarm across Asia.

Immigrant children given adult dose of hepatitis A vaccine

Jul 04, 2015

About 250 immigrant children were given an adult dose of a hepatitis A vaccine at a Texas detention facility where they were being held with their mothers, according to U.S. Immigration and Customs Enforcement officials.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.