New understanding of how we remember traumatic events

October 23, 2008

(PhysOrg.com) -- Neuroscientists at The University of Queensland have discovered a new way to explain how emotional events can sometimes lead to disturbing long term memories.

In evolutionary terms, the brain's ability to remember a fear or trauma response has been crucial to our long term survival.

However, in the modern world, when a similar type of fear response is triggered by a traumatic event such as being in combat; being exposed to abuse or being involved a major car accident, we do not want to repeatedly re-experience the episode, in vivid detail, for the rest of our lives.

During studies of the almond-shaped part of the brain called the amygdala – a region associated with processing emotions – Queensland Brain Institute (QBI) scientists have uncovered a cellular mechanism underlying the formation of emotional memories, which occurs in the presence of a well known stress hormone.

In a scientific paper published in the Journal of Neuroscience, QBI's Dr Louise Faber and her colleagues have demonstrated how noradrenaline, the brain's equivalent of adrenaline, affects the amygdala by controlling chemical and electrical pathways in the brain responsible for memory formation.

“This is a new way of understanding how neurons form long term memories in the amygdala,” Dr Faber said.

“Our strongest and most vivid human memories are usually associated with strong emotional events such as those associated with extreme fear, love and rage.”

“For many of us, our deepest memories are mental snapshots taken during times of high emotional impact or involvement,” she said.

“Some aspects of memory formation are incredibly robust – and the mechanism we've discovered opens another door in terms of understanding how these memories are formed.”

Dr Faber said her team's discovery could help other scientists to elucidate new targets, leading to better treatments for conditions such as anxiety disorders and post-traumatic stress disorder.

Established with the generous support of the Atlantic Philanthropies in 2003 as part of the Queensland Government's Smart State Initiative, QBI is dedicated to understanding the molecular basis of brain function and applying this knowledge to the development of new therapeutics to treat brain and mental health disorders.

Paper: “Modulation of SK channel trafficking by beta adrenoceptors enhances excitatory synaptic transmission and plasticity in the amygdala,” Journal of Neuroscience, 22 October 2008.

Provided by University of Queensland

Explore further: Breakthrough in 'marriage-broker' protein

Related Stories

Breakthrough in 'marriage-broker' protein

August 12, 2015

Scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and the McGill University Health Centre, have made a breakthrough in understanding an important protein that appears to act as ...

Researchers build first working memcomputer prototype

July 6, 2015

(Tech Xplore)—A combined team of researchers from the University of California and Politecnico di Torino in Italy has built, for the first time, a working memory-crunching computer (memcomputer) prototype. It is capable, ...

Rejuvenating the comparative approach in modern neuroscience

July 20, 2015

65 years ago, the famed behavioral endocrinologist Frank Beach wrote an article in The American Psychologist entitled 'The Snark was a Boojum'. The title refers to Lewis Carroll's poem 'The Hunting of the Snark', in which ...

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

(PhysOrg.com) -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.