Diabetes could be a hidden condition for heart disease patients

July 15, 2008

Researchers at the University of Warwick have discovered diabetes could be a hidden condition for some patients with coronary heart disease.

In a study led by Dr Saverio Stranges, Associate Professor of Cardiovascular Epidemiology at Warwick Medical School, the team looked at levels of oxidative stress in the body (a toxic effect which causes cell damage).

They found high levels of oxidative stress in people with coronary heart disease, previously thought to be a marker of the heart condition, could instead indicate a condition of glucose abnormality, such as overt type 2 diabetes.

The research team took blood samples to contrast oxidative stress levels in people with coronary heart disease, people with type 2 diabetes and healthy control subjects. Previous studies have shown people with type 2 diabetes and people with coronary heart disease have high levels of oxidative stress.

Dr Stranges' team expected to produce similar results, but they found that those stress levels were low in people with coronary heart disease but without type 2 diabetes. Further investigation showed people from this group with high levels also had overt type 2 diabetes.

The research used data taken from the Western New York Health Study. This was a case-control study of myocardial infarction and cardiovascular risk factors among residents of Erie and Niagara Counties, New York.

Dr Stranges said: "The results were intriguing. We expected to find high levels of oxidative stress in people with a clinical heart condition, such as myocardial infarction, and people with diabetes. As we thought, the levels were high for diabetics, but there were some discrepancies for people with heart disease.

"Our findings suggest the observed associations of increased oxidative stress in individuals with heart disease may be dependent on underlying abnormalities in glucose metabolism."

Source: University of Warwick

Explore further: Connected sports shirt promises 'smart,' at a price

Related Stories

Supercomputers listen to the heart

August 19, 2015

New supercomputer models have come closer than ever to capturing the behavior of normal human heart valves and their replacements, according to recent studies by groups including scientists at the Institute for Computational ...

Aquariums deliver health and wellbeing benefits

July 29, 2015

People who spend time watching aquariums and fish tanks could see improvements in their physical and mental wellbeing, according to new research published in the journal Environment & Behavior.

Are we born racist? Bias expert answers timely questions

July 28, 2015

Rodolfo Mendoza-Denton, PhD, professor of psychology and Richard & Rhoda Goldman distinguished professor of social sciences at the University of California, Berkeley, recently co-edited a book called Are We Born Racist?: ...

Software turns smartphones into tools for medical research

July 27, 2015

Jody Kearns doesn't like to spend time obsessing about her Parkinson's disease. The 56-year-old dietitian from Syracuse, New York, had to give up bicycling because the disorder affected her balance. But she still works, drives ...

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

(PhysOrg.com) -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.