New technique in treating patients with liver cancer proves effective

Apr 11, 2008

Use of multipolar radiofrequency ablation in the treatment of colorectal liver metastases is effective and has a relatively low recurrence rate, according to a recent study conducted by researchers at Charité, Campus Benjamin Franklin in Berlin, Germany.

“Radiofrequency ablation (RFA) has become a widely used treatment option for patients with primary liver cancer and liver metastases from some primary tumors, if surgery is not an option. However, because of limited sizes of the ablation zones the technique has been limited to tumors smaller than four centimeters,” said Bernd Frericks, MD, lead author of the study.

“This long-term study (four years) was performed using a new multipolar radiofrequency (RF)-device allowing for up to six ablation probes to be used simultaneously, thus providing larger ablation zones. We evaluated this new technique prospectively regarding ablation zone size, technical effectiveness, complications and clinical outcome in patients with colorectal liver metastases,” he said.

The study evaluated 27 patients with 67 colorectal liver metastases that were treated using multipolar RF ablation. According to the study, complete tumor destruction occurred in 66 of 67 cases. Of the 67 metastases, eight required reablation. After a mean of nine months, 16 patients developed new metastases in the liver and the lung, eight of which were successfully reablated. After four years, 52% of the patients are now tumor-free and 78% are still living.

“Using this new device, the rate of local tumor progressions was not influenced by the size of the tumor to be treated,” said Dr. Frericks.

Source: American Roentgen Ray Society

Explore further: Population-based FIT screening can reduce CRC mortality

Related Stories

Herschel's hunt for filaments in the Milky Way

14 minutes ago

Observations with ESA's Herschel space observatory have revealed that our Galaxy is threaded with filamentary structures on every length scale. From nearby clouds hosting tangles of filaments a few light-years ...

Food or fuel? How about both?

14 minutes ago

In the United States, federal mandates to produce more renewable fuels, especially biofuels, have led to a growing debate: Should fuel or food grow on arable land? Recent research shows farmers can successfully, ...

Using desalination to address drought

14 minutes ago

"It's a very interesting time in the water industry," says Carlos Riva '75, CEO of Poseidon Water, a company that is drawing attention as it develops, in Southern California, what will be the largest seawater ...

Recommended for you

Population-based FIT screening can reduce CRC mortality

15 hours ago

(HealthDay)—Population-based fecal immunochemical testing (FIT) screening in adults aged 50 to 69 years can reduce colorectal cancer (CRC) mortality, according to a study published online May 20 in Cancer.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.