New technique in treating patients with liver cancer proves effective

Apr 11, 2008

Use of multipolar radiofrequency ablation in the treatment of colorectal liver metastases is effective and has a relatively low recurrence rate, according to a recent study conducted by researchers at Charité, Campus Benjamin Franklin in Berlin, Germany.

“Radiofrequency ablation (RFA) has become a widely used treatment option for patients with primary liver cancer and liver metastases from some primary tumors, if surgery is not an option. However, because of limited sizes of the ablation zones the technique has been limited to tumors smaller than four centimeters,” said Bernd Frericks, MD, lead author of the study.

“This long-term study (four years) was performed using a new multipolar radiofrequency (RF)-device allowing for up to six ablation probes to be used simultaneously, thus providing larger ablation zones. We evaluated this new technique prospectively regarding ablation zone size, technical effectiveness, complications and clinical outcome in patients with colorectal liver metastases,” he said.

The study evaluated 27 patients with 67 colorectal liver metastases that were treated using multipolar RF ablation. According to the study, complete tumor destruction occurred in 66 of 67 cases. Of the 67 metastases, eight required reablation. After a mean of nine months, 16 patients developed new metastases in the liver and the lung, eight of which were successfully reablated. After four years, 52% of the patients are now tumor-free and 78% are still living.

“Using this new device, the rate of local tumor progressions was not influenced by the size of the tumor to be treated,” said Dr. Frericks.

Source: American Roentgen Ray Society

Explore further: Second-line cetuximab active beyond progression in quadruple wild-type patients with mCRC

Related Stories

Clot-dissolving bubbles to treat strokes?

Sep 25, 2013

(Medical Xpress)—Researchers are using computer simulations to investigate how ultrasound and tiny bubbles injected into the bloodstream might break up blood clots, limiting the damage caused by a stroke ...

Recommended for you

Spicy treatment the answer to aggressive cancer?

Jul 03, 2015

It has been treasured by food lovers for thousands of years for its rich golden colour, peppery flavour and mustardy aroma…and now turmeric may also have a role in fighting cancer.

Cancer survivors who smoke perceive less risk from tobacco

Jul 02, 2015

Cancer survivors who smoke report fewer negative opinions about smoking, have more barriers to quitting, and are around other smokers more often than survivors who had quit before or after their diagnosis, according to a ...

Melanoma mutation rewires cell metabolism

Jul 02, 2015

A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme, researchers at Winship Cancer Institute of Emory University have discovered.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.