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Genetics
Algorithm pinpoints potential disease-causing variants in non-coding regions of human genome
Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which ...
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Medical research news
Genetic variant reveals how cleft lip and cleft palate can arise
Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United States. These defects, which appear when the tissues that form the lip or the roof of the mouth do not ...
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Personalized predictive model improves risk assessment for coronary artery disease
Coronary artery disease (CAD) is the leading cause of death in the United States. Although effective preventive treatments exist, these measures are often underutilized, in part because people don't know they're at risk of ...
27 minutes ago
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Healthy sleep patterns decrease the risk of being hospitalized for infections, study finds
Sleep is an essential biological process known to contribute to both mental and physical health. In addition to supporting memory processes and learning, boosting concentration, facilitating the body's recovery, and promoting ...
A common diabetes drug may prevent leukemia, mouse study suggests
Metformin, a widely used and affordable diabetes drug, could prevent a form of acute myeloid leukemia in people at high risk of the disease, a study in mice has suggested. Further research in clinical trials will be needed ...
2 hours ago
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Mouse model reveals how the Icelandic mutation protects against Alzheimer's disease
RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in animals for the first time. This could eventually lead to the development of new ways to treat the neurodegenerative ...
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How to prime tumors to be defeated by cancer immunotherapy
One of the best ways to defeat cancer is by rousing the immune system to attack it.
4 hours ago
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A changing climate may jeopardize global blood supply
A new study published in The Lancet Planetary Health suggests a changing climate threatens the continuous availability of safe blood across the world.
17 hours ago
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Start of US hunting season linked to increased firearm incidents, including violent crimes and suicide
The start of deer hunting season in the US—when firearms and ammunition are more available in certain states—is associated with increases in both hunting and non-hunting-related firearm incidents, including violent crime ...
17 hours ago
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Scientists achieve record-breaking growth in miniature, functional liver models
The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is thought to be affected by conditions ...
20 hours ago
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Even vegans who get enough total protein may fall short for some essential amino acids, findings suggest
In a new study of people with long-term vegan diets, most ate an adequate amount of total daily protein, but a significant proportion did not meet required levels of the amino acids lysine and leucine. Bi Xue Patricia Soh ...
21 hours ago
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Stem cell therapy potentially a safe and effective way to treat Parkinson's disease
Two independent clinical trials demonstrate the safety of stem cell therapies for Parkinson's disease. The papers, published in Nature this week, investigate the use of cells derived from human induced pluripotent stem cells ...
23 hours ago
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Pushing the limits of brain imaging: A new tool for targeted delivery of imaging agents and drugs
Multiphoton microscopy is a valuable tool for neuroscience research, allowing scientists to observe functional brain activity in real time through high-resolution imaging. An essential component of many multiphoton microscopy ...
20 hours ago
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Psycho-social therapies found to be most effective treatments for unexplained abdominal pain in children
Hypnotherapy and cognitive behavioral therapy (CBT) are the most effective treatments for children suffering with unexplained abdominal pain, according to new research published today in The Lancet Child & Adolescent Health.
23 hours ago
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Reprogramming cancer cells to treat an aggressive type of leukemia
A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.
23 hours ago
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Emerging metabolic pathways in osteoarthritis: Insights from recent studies and therapeutic avenues
Osteoarthritis (OA) is one of the most prevalent conditions affecting tens of millions of U.S. adults, traditionally understood as a disease driven primarily by mechanical wear and tear. This perspective is being reshaped ...
23 hours ago
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New human 'multi-zonal' liver organoids improve injury survival in rodents
One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key "zones" that perform specific major tasks. So, if scientists hope to create self-growing patches of ...
23 hours ago
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Risky surgery after a stroke due to carotid artery stenosis may no longer be necessary in most patients
European research led by University College London (UCL), together with Amsterdam UMC and the University of Basel, shows that a significant proportion of patients who suffer a stroke due to carotid artery narrowing can be ...
17 hours ago
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How long can you stand on one leg? This simple test is the single clearest indicator of physical aging
Balance is so fundamental that we often take it for granted, but its importance goes far beyond just keeping us upright. In fact, recent studies have shown that the ability to stand on one leg may be one of the best physical ...
20 hours ago
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