Unusual flu vaccine is developed

Jun 14, 2006

U.S. scientists have used reverse genetics to develop an influenza virus with two key proteins on its surface derived from the H5N1 avian virus strain.

As nations stockpile vaccines against H5N1, the strain of influenza virus that experts fear could cause the next flu pandemic, researchers are unsure if the vaccines will remain effective as the virus mutates.

Dr. Elena Govorkova, Robert Webster and colleagues at St. Jude Children's Research Hospital in Memphis, say they inactivated the virus and used it to vaccinate ferrets.

They said the vaccine protected ferrets from becoming sick when exposed not only to the flu strain from which the vaccine was made, but also two other strains, including a deadly strain labeled A/Vietnam/1203/04.

Cross-strain protection is what would been needed in a pandemic, since it would protect against newly emerging variants until a strain-specific vaccine could be developed.

The scientists said the reverse genetics method they used would allow rapid vaccine preparation, which would be crucial in a fast-moving pandemic.

The study will appear in the July 15 issue of The Journal of Infectious Diseases and is available online.

Copyright 2006 by United Press International

Explore further: CKD, glomerulonephritis risk higher for those with psoriasis

add to favorites email to friend print save as pdf

Related Stories

African swine fever threatens Europe

Dec 17, 2014

African swine fever, or ASF, is a viral disease that kills almost every pig it infects and is likened to Ebola. It gained a foothold in Georgia in 2007, when contaminated pig meat landed from a ship from ...

X-rays show how flu antibody binds to viruses

Dec 09, 2014

An important study conducted in part at the Department of Energy's SLAC National Accelerator Laboratory may lead to new, more effective vaccines and medicines by revealing detailed information about how a ...

Recommended for you

Older women restrict driving more than older men

4 hours ago

(HealthDay)—Older women restrict their driving activity more than older men, regardless of physical health or cognitive status, according to a study published in the November issue of the Journal of th ...

Sublingual immunotherapy tablet safe in asthma patients

4 hours ago

(HealthDay)—For individuals with asthma and allergic rhinitis with/without conjunctivitis (AR/C), treatment with a Timothy grass sublingual immunotherapy tablet (SLIT-tablet) seems safe, according to research ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.