Unusual flu vaccine is developed

Jun 14, 2006

U.S. scientists have used reverse genetics to develop an influenza virus with two key proteins on its surface derived from the H5N1 avian virus strain.

As nations stockpile vaccines against H5N1, the strain of influenza virus that experts fear could cause the next flu pandemic, researchers are unsure if the vaccines will remain effective as the virus mutates.

Dr. Elena Govorkova, Robert Webster and colleagues at St. Jude Children's Research Hospital in Memphis, say they inactivated the virus and used it to vaccinate ferrets.

They said the vaccine protected ferrets from becoming sick when exposed not only to the flu strain from which the vaccine was made, but also two other strains, including a deadly strain labeled A/Vietnam/1203/04.

Cross-strain protection is what would been needed in a pandemic, since it would protect against newly emerging variants until a strain-specific vaccine could be developed.

The scientists said the reverse genetics method they used would allow rapid vaccine preparation, which would be crucial in a fast-moving pandemic.

The study will appear in the July 15 issue of The Journal of Infectious Diseases and is available online.

Copyright 2006 by United Press International

Explore further: Mali announces new Ebola case

add to favorites email to friend print save as pdf

Related Stories

A digital version of you

Mar 12, 2014

When NASA's Mars Rover Opportunity sends a photograph of the alien landscape back to Earth, it relays the information as digital data, a series of ones and zeros that computers assemble into pictures that ...

Recommended for you

Mali announces new Ebola case

15 hours ago

Mali announced Saturday a new case of Ebola in a man who is fighting for his life in an intensive care unit in the capital Bamako.

Plague outbreak kills 40 in Madagascar: WHO

15 hours ago

An outbreak of plague has killed 40 people in Madagascar, the World Health Organization said, warning that the disease could spread rapidly in the country's densely populated capital Antananarivo.

Structured education program beneficial for anaphylaxis

Nov 21, 2014

(HealthDay)—A structured education intervention improves knowledge and emergency management for patients at risk for anaphylaxis and their caregivers, according to a study published online Nov. 19 in Allergy.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.