Human chromosome 3 is sequenced

Apr 27, 2006

The sequencing of human chromosome 3 at Baylor College represents the final stage of a multi-year project to sequence the human genome.

The researchers at the Baylor College of Medicine Human Genome Sequencing Center say they are now using the information to discover the genetic basis for human disease.

Sequencing chromosome 3 was an international collaboration among teams from the United States. Germany and The People's Republic of China.

The lead author of the paper was BCM scientist Donna Muzny, but she and Dr. Steven Scherer, associate professor in the BCM Human Genome Sequencing Center, credit Dr. Huanming Yang and the Chinese sequencing group with playing a critical role in the effort.

Yang and colleagues at the Beijing Genomes Institute of the Chinese Academy of Sciences determined the DNA sequence of a portion of the chromosome and characterized important elements that regulate how the DNA is translated into proteins critical to the functioning of the cell.

The BCM Sequencing Center has produced the sequences of chromosomes 3, 12 and X -- about 10 percent of the human genome.

The research appears in the journal Nature, in which the sequences of the other two chromosomes appeared in earlier reports.

Copyright 2006 by United Press International

Explore further: School scoliosis screening has sustained effectiveness

Related Stories

Chromosome-folding theory shows promise

Apr 28, 2015

Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.

Recommended for you

Bacteria blamed in indigenous Mexican baby deaths

7 hours ago

Bacteria—and not a contaminated vaccine as initially suspected—were to blame for the recent deaths of two Mexican babies and for sickening 29 others, according to an official investigation.

German woman, 65, gives birth to quadruplets

7 hours ago

A 65-year-old teacher from Berlin has given birth to quadruplets after a pregnancy that was widely criticized by medical professionals because of her age, RTL television said Saturday.

US appeals court upholds delay in Alzheimer's drug swap

22 hours ago

A federal appeals court has rejected a drug manufacturer's appeal and affirmed a judge's order that Actavis PLC keep distributing its widely used Alzheimer's medication until after its patent expires this summer.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.