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Medications
Disparities in direct oral anticoagulant initiation have declined in recent years: Study
Historical disparities in initiation of direct oral anticoagulants (DOACs) for atrial fibrillation have lessened for Black and Hispanic patients, according to a study published online May 6 in JAMA Network Open.
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Diseases, Conditions, Syndromes
Thrombectomy linked to better outcomes for acute stroke, large infarct
For patients with acute stroke and a large infarct, thrombectomy plus medical care results in better functional outcomes and lower mortality, according to a study published in the May 9 issue of the New England Journal of ...
May 9, 2024
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Bariatric surgery tied to higher short-term risk for venous thromboembolism
In the short term, bariatric surgery is associated with a greater risk for venous thromboembolism (VTE), but in the long-term, it is associated with lower risk, according to a study published online April 30 in Obesity Surgery.
May 9, 2024
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About 90% of US adults are on the way to heart disease, study suggests
Nine of 10 American adults are in the early, middle or late stages of a syndrome that leads to heart disease, a new report finds, and almost 10% have the disease already.
May 8, 2024
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Intervention in Navajo Nation boosts uptake for heart failure drugs by 53%
A team led by LDI senior fellow and Perelman School of Medicine faculty member Lauren Eberly at a Navajo Nation hospital in New Mexico has developed a simple intervention that increased the uptake of guideline-directed heart ...
May 8, 2024
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Discovery of key target for precision pharmacology makes ideal candidate to treat heart failure
Researchers at the University of Houston College of Pharmacy have discovered that when a higher amount of a protein called AKAP12 is present inside the heart, it speeds up the work of an enzyme called PDE8A and can accelerate ...
May 8, 2024
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Hypertensive disorders of pregnancy may increase women's risk for blood clots later in life
South Carolina received a poor report card from the March of Dimes in 2023 because more of its mothers die due to pregnancy-related complications or childbirth than the national average. For every 100,000 births, there are ...
May 8, 2024
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Simulated high-altitude exposure for 24 hours is well tolerated despite single-ventricle physiology
A long-haul flight or an overnight stay in the mountains: For many patients with a Fontan circulation (single-ventricle physiology), this was previously unimaginable, as there was insufficient medical research into how acute ...
May 8, 2024
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Exercise, new drug class recommended for management of hypertrophic cardiomyopathy
The American College of Cardiology (ACC) and the American Heart Association (AHA) have released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline ...
May 8, 2024
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Team systematically modifies glyceraldehyde derivative JX22 for improved anti-heart failure efficacy and safety
Sodium-glucose cotransporter 2 inhibitors are a class of glucose-lowering drugs known for robust cardiovascular protective properties. However, the side effects induced by sodium-glucose cotransporter 2 inhibition limit application ...
May 8, 2024
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Potential causal effect of long-term PM₁ exposure on hypertension hospitalization
Hypertension is among the leading cardiovascular diseases. Despite extensive research, evidence concerning the relationship between long-term exposure to ambient particulate matter and hypertension remains limited and inconsistent, ...
May 8, 2024
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AI may help physicians detect abnormal heart rhythms earlier
An artificial intelligence program developed by investigators in the Smidt Heart Institute and their Cedars-Sinai colleagues can detect a type of abnormal heart rhythm that can go unnoticed during medical appointments, according ...
May 7, 2024
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Biomarker found to help identify cells that can repair damaged blood vessels
Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings, recently published in Circulation, could lead to new therapies for people with ...
May 7, 2024
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Small pump for kids awaiting heart transplant shows promise in new trial
A small, implantable cardiac pump that could help children await heart transplants at home, not in the hospital, has performed well in the first stage of human testing.
May 7, 2024
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Sedentary lifestyle puts strain on young hearts, study shows
According to a recent Finnish study, high levels of sedentary behavior and physical inactivity from childhood strain the heart in adolescence. High cardiac workload predicts heart failure and other heart diseases. In light ...
May 7, 2024
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Childhood sedentariness linked to premature heart damage: Light physical activity reverses risk, study shows
An increase in sedentary time from childhood causes progressing heart enlargement, a new study shows. However, light physical activity could reduce the risk. The study was conducted in collaboration among the Universities ...
May 7, 2024
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Microscopic heart vessels imaged in super-resolution for the first time
Researchers from Imperial College London's Department of Bioengineering and Faculty of Medicine worked alongside academics from UCL to produce sub-millimeter resolution images of cardiac micro-vessels. The non-invasive new ...
May 6, 2024
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Risk for 'most' cardiovascular diseases no higher with inflammatory bowel disease, study finds
Among postmenopausal women with inflammatory bowel disease (IBD), there is no higher risk for cardiovascular disease (CVD) compared with women without IBD, although the risk for ischemic stroke may be higher, according to ...
May 6, 2024
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Personalized screening early in pregnancy may improve preeclampsia detection
A new screening algorithm for preeclampsia combining maternal history, ultrasound data and several tests for blood markers may better predict the majority of preeclampsia cases in the first trimester of pregnancy, when it ...
May 6, 2024
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Key therapy equally effective for women, men with narrowed leg arteries
Peripheral artery disease (PAD) involves a debilitating narrowing of arteries in the legs, and the National Institutes of Health estimates that one in every 20 Americans over 50 is affected.
May 6, 2024
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