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TSU has created the most durable porous material for bone replacement

February 12th, 2020 Elena Fritz

The staff of the Laboratory of Medical Alloys and Implants with Shape Memory at the TSU Siberian Institute of Physics and Technology has completed testing the porous alloy SHS-TiNi. The study of modified titanium nickelide, created for the manufacture of implants, showed its high biocompatibility and its maximum resistance to cyclic loads for porous materials. The next step will be technical and toxicological certification testing.

- Titanium nickelide is one of the most well-known materials with shape memory effect and is widely used in medicine, - says Ekaterina Marchenko, a senior researcher at the Laboratory of Medical Alloys and Implants with Shape Memory. - We got an alloy with high corrosion resistance. The functional characteristics were improved by modifying the gas medium in which the alloy is synthesized.

The biomechanical properties of the material were tested using quasi=static tension and bending. This study enabled the TSU scientists to argue that the deformation behavior of porous titanium nickelide, like the behavior of a monolithic alloy, is viscoelastic and similar to the rheology of biological tissues.

In endurance tests, 70% of the SHS-TiNi alloy samples withstood 1 million deformation cycles without fracture, which is the best result for porous corrosion-resistant materials. Along with this, a series of experiments involving laboratory animals was conducted in one of the Russian medical centers. The results confirmed the high survival rate of the modified nickelide.

The high endurance and biological inertness of the porous alloy proven in preclinical trials will enable using this material in new surgical techniques in oncology and traumatology when replacing extensive defects in bone structures. The next stage of work will be the technical and toxicological certification tests necessary for utilizing the material in surgical practice.

More information:
www.ncbi.nlm.nih.gov/pmc/articles/PMC6696327/

Provided by Tomsk State University

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