Creature the size of a dust grain found hiding in California's Mono Lake

University of California, Berkeley researchers have now found another unusual creature lurking in the lake's briny shallows—one that could tell scientists about the origin of animals more than 650 million years ago.

The organism is a choanoflagellate, a microscopic, single-celled form of life that can divide and develop into multicellular colonies in a way that's similar to how animal embryos form. It's not a type of animal, however, but a member of a sister group to all animals. And as animals' closest living relative, the choanoflagellate is a crucial model for the leap from one-celled to multicellular life.

Surprisingly, it harbors its own microbiome, making it the first choanoflagellate known to establish a stable physical relationship with bacteria, instead of solely eating them. As such, it's one of the simplest organisms known to have a microbiome.

"Very little is known about choanoflagellates, and there are interesting biological phenomena that we can only gain insight into if we understand their ecology," said Nicole King, a UC Berkeley professor of molecular and and a Howard Hughes Medical Institute (HHMI) investigator who studies choanoflagellates as a model for what early life was like in ancient oceans.

A colony of choanoflagellates stained to show its features. Cyan indicates DNA—the doughnut-shaped DNA of the choanoflagellate cells and a cloud of bacterial DNA inside the colony—while flagella are white and microscopic hairs (villi) on each cell are red. Credit: Kayley Hake, Nicole King lab, UC Berkeley

Globular colonies of the choanoflagellate B. monosierra seen under a microscope. As indicated by the 50-micron scale bar, these colonies are at the limit of what's visible to the naked eye. Credit: Alain Garcia De Las Bayonas, Nicole King lab

A 3D reconstruction of a spherical colony of 70 choanoflagellates from the newly-named species Barroeca monosierra discovered in Mono Lake. Colonies of these organisms consist of numerous identical cells (cyan), each with flagella (orange) that allow them to propel themselves through the water. This choanoflagellate colony hosts its own microbiome, something never before seen in these organisms. Credit: Davis Laundon and Pawel Burkhardt, Sars Centre, Norway; Kent McDonald and Nicole King, UC Berkeley