New research tool targets microRNA expression in zebrafish

A new research tool for studying microRNA expression in zebrafish will help researchers study the effects of miRNA on the early development of this model organism and better understand developmental and disease mechanisms ...

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

How cytoplasm separates from yolk

The segregation of yolk from the surrounding cytoplasm in the very early fish embryo is a key process for the development of fish larva. To identify its underlying mechanisms, biologists at the Institute of Science and Technology ...

A mutated eye offers a glimpse of a key protein for preventing cancer

About 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in significantly smaller eyes than those of wild zebrafish. Now, one of these researchers—Prof. ...

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