Study answers longstanding cell-development riddle

During the lifetime of a body—whether human, fish or any other type of vertebrate—cells die, making room for fresh new cells to carry on vital processes. The dead cells must be cleared away, though, and debris removal ...

Patchwork-like image of developing zebrafish sensory organ

This image may bring to mind a patchwork quilt, or a picture taken from a gallery of abstract paintings, but the artisan behind it is actually Mother Nature, with a little help from scientists at the European Molecular Biology ...

Histone modifications are the influencers of zygotic genome awakening

The zebrafish is an important model organism in biology. Humans and zebrafish share 70 percent of their genes, and more than 80 percent of human genes associated with disease are known to have a zebrafish counterpart. Additionally, ...

When a fish becomes fluid

Zebrafish aren't just surrounded by liquid, but turn liquid—in part—during their development. As the zebrafish embryo develops from a ball of cells to a fully-formed fish, a region of the embryo switches its phase from ...

Patterns in primordial germ cell migration

Whenever an organism develops and forms organs, a tumor creates metastases or the immune system becomes active in inflammation, cells migrate within the body. As they do, they interact with surrounding tissues which influence ...

New research tool targets microRNA expression in zebrafish

A new research tool for studying microRNA expression in zebrafish will help researchers study the effects of miRNA on the early development of this model organism and better understand developmental and disease mechanisms ...

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

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