Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

Fungal compound inhibits important group of proteins

Researchers in the group of Jeroen den Hertog, in collaboration with researchers in Leiden, have found that a compound inhibits a group of proteins called BMP receptors. This compound, called cercosporamide, was previously ...

Using fungi to search for medical drugs

An enormous library of products derived from more than 10,000 fungi could help scientists find new drugs. Researchers from the group of Jeroen den Hertog at the Hubrecht Institute, in collaboration with researchers from the ...

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