Embryonic tissue undergoes phase transition

When scientists at the Institute of Science and Technology (IST) Austria looked at developing zebrafish embryos, they observed an abrupt and dramatic change: Within just a few minutes, the solid-like embryonic tissue becomes ...

Patterns in primordial germ cell migration

Whenever an organism develops and forms organs, a tumor creates metastases or the immune system becomes active in inflammation, cells migrate within the body. As they do, they interact with surrounding tissues which influence ...

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

Fungal compound inhibits important group of proteins

Researchers in the group of Jeroen den Hertog, in collaboration with researchers in Leiden, have found that a compound inhibits a group of proteins called BMP receptors. This compound, called cercosporamide, was previously ...

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