News tagged with xist

Understanding X-chromosome silencing in humans

Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. X-chromosome silencing is essential for proper development ...

dateDec 15, 2016 in Biotechnology
shares118 comments 0

Tags on RNA silence X chromosome in females

The addition of a chemical tag on an RNA molecule is the critical switch that inactivates one X chromosome in every cell, ensuring healthy development in all female mammals, according to new research by Weill Cornell Medicine ...

dateSep 19, 2016 in Biotechnology
shares23 comments 0

Hushing the X chromosome

Early in the development of female embryos, a crucial event occurs in all cells: An X chromosome is silenced. Whereas males have only one X chromosome, females have two—which means they can have twice as many proteins generated ...

dateAug 08, 2016 in Biotechnology
shares49 comments 0

How an RNA gene silences a whole chromosome

Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified ...

dateApr 27, 2015 in Biotechnology
shares76 comments 1

Scientists unveil sex-linked control of genes

Many proteins interact with an RNA molecule called Xist to coat and silence one X chromosome in every female cell. Learning how genes are targeted and silenced may help researchers studying sex-specific diseases.

dateApr 03, 2015 in Biotechnology
shares208 comments 26