A 'rheostat' for cancer signals

WNT signaling pathways play important roles in cell growth, development and cancer. The classical or "canonical" WNT pathway and its atypical, "non-canonical" counterpart share a protein called DVL2 that "transduces" or converts ...

Surprising signal to control male fertility

Signaling molecules of the Wnt family are ubiquitous in biology. From cnidaria to man, they are responsible for forming the basic shape of all organisms. Without Wnt, our body would not have a top or bottom, front or rear. ...

One step closer to cell reprogramming

In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar ...

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