Detailed map shows how viruses infect humans

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...

Dynamics of key viral attack strategy visible for first time

Many infectious viruses, from HIV to West Nile, rely on a fundamental biological process called frameshifting to maximize their attack. Long identified as a key mechanism that viruses use to proliferate inside their hosts, ...

Snapshots of the flu virus replication machine in action

Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, ...

Cell-killing proteins suppress listeria without killing cells

New North Carolina State University research shows that key proteins known for their ability to prevent viral infections by inducing cell death can also block certain bacterial infections without triggering the death of the ...

How viruses outsmart their host cells

Viruses depend on host cells for replication, but how does a virus induce its host to transcribe its own genetic information alongside that of the virus, thus producing daughter viruses? For decades, researchers have been ...

Super-resolution microscope reveals secrets of deadly Nipah virus

The deadly Nipah virus and others like it assemble themselves in a much more haphazard manner than previously thought, new UBC research has found. The discovery could allow scientists to develop more effective vaccines and ...

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