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A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

dateMar 28, 2017 in Biotechnology
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Lethal reawakening

Retroviral DNAs integrate into host genomes, but their expression is normally repressed by cellular defense mechanisms. As an Ludwig-Maximilians-Universitaet (LMU) in Munich team now shows, when these measures fail, accumulation ...

dateMay 17, 2016 in Biotechnology
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