New microcapsules to enhance the efficiency of genome-editing

Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have found that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when ...

Restricting HIV-1 infection

The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that ...

Study reveals mechanisms of fighting pathogenic viruses

Researchers of the KFU Omics Lab have succeeded in deciphering a Phi29-family virus genome. Junior researcher Raihan Shah Mahmud of Kazan Federal University says, "There is an immense number of viruses in nature, hundreds ...

A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

Compact CRISPR systems found in some of world's smallest microbes

UC Berkeley scientists have discovered simple CRISPR systems similar to CRISPR-Cas9—a gene-editing tool that has revolutionized biology—in previously unexplored bacteria that have eluded efforts to grow them in the laboratory.

Hijacked cell division helped fuel rise of fungi

A new study finds that the more than 90,000 species of mushrooms, molds, yeasts and other fungi found everywhere in the soil, water and air may owe their abilities to grow, spread, and even cause disease to an opportunistic ...

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