Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease. While some proteins must be synthesized at specific times, others require timely breakdown ...
Cell & Microbiology
Sep 21, 2023
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32
Which structures do complex proteins adopt in solution? Konstanz biophysicists answer this question using the example of ubiquitin dimers as well as a new combination of high-resolution NMR spectroscopy and sophisticated ...
Cell & Microbiology
Aug 22, 2023
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63
The small protein ubiquitin is particularly famous for marking proteins for degradation but it has also been shown to regulate virtually all cellular processes. In parallel to the ubiquitin system various other ubiquitin-like ...
Biochemistry
Aug 11, 2023
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100
By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.
Biochemistry
Feb 15, 2023
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90
In a study published in The Plant Cell, researchers led by Li Yunhai at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences described a role for the endoplasmic reticulum (ER)–associated ...
Cell & Microbiology
Feb 10, 2023
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22
In plants, the phytohormone abscisic acid (ABA) plays a vital role in repressing seed germination and subsequent early seedling establishment, and ABA-INSENSITIVE 3 (ABI3) and ABI5 are two essential regulators of these developmental ...
Plants & Animals
Feb 7, 2023
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8
A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.
Biochemistry
Nov 14, 2022
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283
The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
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32
In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed.
Cell & Microbiology
Oct 6, 2022
0
102
Researchers at the Rudolf Virchow Center of the University of Würzburg have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to ...
Cell & Microbiology
Sep 9, 2022
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