Exotic signaling mechanism in pathogens

The unicellular parasite that causes sleeping sickness differs from other eukaryotes in the mode of regulation of an essential cellular signaling pathway. This provides a promising point of attack for drug development.

Viral communications hacking boosts Leishmania infections

New research from McGill University has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against ...

Discovery aids disease elimination efforts

Researchers at the University of Dundee have identified a new drug target in parasites that cause major neglected tropical diseases, a discovery that contributes towards a global drive to eliminate these diseases by 2030.

Sugar withdrawal—killing the leishmania parasite

Findings on how parasites cope with stress on a cellular level could aid the development of drugs that combat leishmaniasis, a tropical disease neglected by the pharmaceutical industry.

Disease poses risk to chimpanzee conservation, study finds

Infectious disease should be a key consideration in wildlife conservation, suggests a study focused on primates in Tanzania's Gombe Stream National Park, published by PLOS Neglected Tropical Diseases. The study investigated ...

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