Research team spins the Sleeping Beauty transposase

EMBL scientists have developed a new variant of the so-called Sleeping Beauty transposase. It has dramatically improved biochemical features, including enhanced stability and intrinsic cell penetrating properties. This transposase ...

Upcycling of proteins protects DNA from parasites

Of the three billion base pairs in the human genome, less than two percent contain the information encoding the ~20,000 proteins. That is, because at least half of our genetic material originated from selfish genetic elements ...

Key protein providing defense against 'jumping genes' identified

Though they occasionally play a role in animal development, transposons, also known as "jumping genetic elements," are in fact DNA sequences that have the potential to move to new positions within the genome. They constitute ...

Understanding how to control 'jumping' genes

A team of Texas A&M University and Texas AgriLife Research scientists have made a new discovery of how a single protein, Serrate, plays dual roles in controlling jumping genes.

Not junk: 'Jumping gene' is critical for early embryo

A so-called "jumping gene" that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development, according to a new study in mice led ...

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