Why transporters really matter for cell factories

In a new study published in PNAS, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) explored how different cell membrane transporters impact the production of dicarboxylic acids.

Fitting a right hand in a left-handed mitten

Many biomolecules come in two versions that are each other's mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins, and uptake mechanisms were thought to ...

Multiple modes for selectivity of transmembrane transport

LMU researchers utilized a biophysical approach to understand how bacterial import proteins bind and selectively convey their cargoes across membranes. The results reveal an unexpectedly wide variety of transfer mechanisms.

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