Why transporters really matter for cell factories

In a new study published in PNAS, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) explored how different cell membrane transporters impact the production of dicarboxylic acids.

Fitting a right hand in a left-handed mitten

Many biomolecules come in two versions that are each other's mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins, and uptake mechanisms were thought to ...

Multiple modes for selectivity of transmembrane transport

LMU researchers utilized a biophysical approach to understand how bacterial import proteins bind and selectively convey their cargoes across membranes. The results reveal an unexpectedly wide variety of transfer mechanisms.

How proteins are assigned to specific transporters

A fundamental cellular mechanism ensures that proteins are transported to the places they are needed in the cells. So-called vesicles are responsible for that transport. Determining their composition has been difficult up ...

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