Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...
Cell & Microbiology
Nov 19, 2018
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70
Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate the process by which ...
Cell & Microbiology
Jan 17, 2013
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0
During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.
Molecular & Computational biology
Feb 26, 2024
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14
Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...
Evolution
Nov 24, 2023
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260
In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral fellow in Shilatifard laboratory, ...
Cell & Microbiology
Nov 3, 2023
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66
The different cell types of the human gut develop from stem cells through a process of differentiation. Researchers from the Organoid group (Hubrecht Institute), together with researchers at the Princess Máxima Center and ...
Cell & Microbiology
Oct 30, 2023
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35
The intricate interplay of gene expression within living cells is akin to a well-orchestrated symphony, with each gene playing its part in perfect harmony to ensure cells function as they should. At the heart of this symphony ...
Cell & Microbiology
Sep 19, 2023
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135
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin have revealed how cells accelerate changes to their identity, ...
Cell & Microbiology
Jun 27, 2023
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58
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
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51
Jumping genes, or transposons, are sections of DNA that can copy themselves and jump between different parts of the genome, and might help plants adapt to stressful, changing conditions, according to a study published in ...
Plants & Animals
Jun 15, 2023
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