An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.
Biochemistry
Oct 15, 2015
0
358
Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres that protect the ends ...
Molecular & Computational biology
Feb 28, 2024
0
244
For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented ...
Molecular & Computational biology
Oct 3, 2022
0
2302
As the rope of a chromosomes replicates, it frays at the ends. No problem: A chromosome's ends have extra twine so that fraying doesn't reach into the body of the rope where the important information resides. This extra twine ...
Cell & Microbiology
Aug 18, 2016
0
1548
More than 30 years ago, when University of California, Berkeley researchers discovered telomerase—an enzyme that lengthens chromosome ends and prevents them from fraying enough to kill a cell—speculation ran wild about ...
Biochemistry
Apr 25, 2018
0
1034
One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: ...
Biochemistry
Mar 3, 2020
2
962
The Wake Forest Institute for Regenerative Medicine (WFIRM) researchers, who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the ...
Cell & Microbiology
Jun 28, 2022
2
687
ASU scientists, together with collaborators from the Chinese Academy of Sciences in Shanghai, have published today, in Nature Structural and Molecular Biology, a first of its kind atomic level look at the enzyme telomerase ...
Cell & Microbiology
May 4, 2014
1
0
Small furry mammals partial to a daily dose of hibernation in winter are probably extending their lifespan at the same time, according to a study published Wednesday.
Plants & Animals
Sep 14, 2011
0
0
The oldest living organism on Earth is a plant, Methuselah a bristlecone pine (Pinus longaeva) that is over 5000 years old. Conversely, animals only live up to a few hundred years. Can we learn something from plants about ...
Molecular & Computational biology
Nov 18, 2019
1
195
